Publications by authors named "Erika M Balfour"
We report a rare case of necrobiotic xanthogranuloma (NXG) of the extremities with paraproteinemia and without periorbital involvement at presentation in a 58-year-old white woman. A combination of oral cyclophosphamide and oral dexamethasone was attempted, but the patient then developed a left intraorbital lesion. Treatment was not successful in that the gammopathy did not improve and the patient continued to develop more lesions.
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- Lichen planopilaris and traction alopecia are types of scarring alopecias, but they have different underlying causes; lichen planopilaris is linked to an autoimmune response, while traction alopecia is caused by mechanical stress.
- A study compared the ratio of Langerhans cells (involved in immune responses) to T lymphocytes in both conditions and found a higher ratio in lichen planopilaris, indicating a stronger immune component.
- The findings suggest that existing classifications of alopecia might need updating, particularly considering that some cases of traction alopecia show immune response similarities, requiring more detailed clinical evaluation.
Background: Sezary syndrome (SS) is an erythrodermic cutaneous T-cell lymphoma with a leukemic component. Biopsies from these patients may suggest erythrodermic mycosis fungoides or SS but most often are not diagnostic. Additional methods are therefore usually needed to diagnose SS.
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