Publications by authors named "Erika K Schonher"
Bioconjug Chem
November 2019
Article Synopsis
- ProGlo is a specialized MRI contrast agent that targets the progesterone receptor (PR) but has solubility issues due to its hydrophobic nature, limiting its clinical use.
- A new formulation using nanodiamond (ND) clusters has improved ProGlo's water solubility and allows for greater release and delivery to target cells without harmful solvents.
- Testing shows that the ND-ProGlo construct effectively delivers ProGlo to PR-positive tissues, outperforming standard methods and advancing the potential for better MRI imaging techniques.
