Biomarkers.

Background: Repetitive head impacts (RHI) from contact sports can lead to long-term white matter injury visualized on FLAIR scans as white matter hyperintensities (WMH). The goal of this study was to preliminarily characterize the unique pattern and features of WMH in middle aged- to older adults with remote history of exposure to RHI from contact sports.

Method: 76 participants (38 with substantial RHI, 38 with minimal or no RHI) from the Boston University Alzheimer's Disease Research Center had a FLAIR MRI during their annual study visit.

Neuropsychological Function in Migraine Headaches: An Expanded Comprehensive Multidomain Meta-Analysis.

Background And Objectives: A sizable literature has studied neuropsychologic function in persons with migraine (PwM), but despite this, few quantitative syntheses exist. These focused on circumscribed areas of the literature. In this study, we conducted an expanded comprehensive meta-analysis comparing performance on clinical measures of neuropsychological function both within and across domains, between samples of PwM and healthy controls (HCs).