Serological prevalence of SARS-CoV-2 infection among prison system workers in the state of Espírito Santo, Brazil, 2020.

Objective: To estimate the serological prevalence of SARS-CoV-2 infection among prison system workers in the state of Espírito Santo, Brazil, between August-September 2020.

Methods: This was a stratified sample survey, using interviews and serological tests for SARS-CoV-2.

Results: Among the 986 interviewers, the serological prevalence of SARS-CoV-2 infection was 11.

Prevalence of COVID-19 infection in the prison system in Espírito Santo/Brazil: persons deprived of liberty and justice workers.

Objective: To present a prevalence study held in prisons and estimate the percentage of persons deprived of liberty, health professionals, and prison officers infected with SARS-CoV-2 in Espírito Santo (ES).

Methods: This is a prevalence study with a sample from 34 ES prisons, stratified between August 31 and September 4, 2020, following the Population-based age-stratified seroepidemiological investigation protocol for COVID-19 virus infection. The participants were interviewed and underwent rapid tests to detect immunoglobulin G and M in the groups mentioned.

Donor natural killer cell allorecognition of missing self in haploidentical hematopoietic transplantation for acute myeloid leukemia: challenging its predictive value.

We analyzed 112 patients with high-risk acute myeloid leukemia (61 in complete remission [CR]; 51 in relapse), who received human leukocyte-antigen (HLA)-haploidentical transplants from natural killer (NK) alloreactive (n = 51) or non-NK alloreactive donors (n = 61). NK alloreactive donors possessed HLA class I, killer-cell immunoglobulin-like receptor (KIR) ligand(s) which were missing in the recipients, KIR gene(s) for missing self recognition on recipient targets, and alloreactive NK clones against recipient targets. Transplantation from NK-alloreactive donors was associated with a significantly lower relapse rate in patients transplanted in CR (3% versus 47%) (P > .