Publications by authors named "Erik Zerath"

Article Synopsis
  • The study analyzed emergency medical services (EMS) data in a region of Israel affected by multiple military conflicts from 2008 to 2021, focusing on the impact of rocket attacks on civilian EMS utilization patterns.
  • Findings indicated significant decreases in EMS call volumes for "medical illness" and "motor vehicle collisions" during conflicts, with notable reductions in advanced life support dispatches, but call volumes rebounded to pre-conflict levels after ceasefires.
  • The consistent drop in call numbers during conflicts suggests a potential habituation of the population to emergency situations, particularly evident in the absence of change during the 2014 conflict.
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Background: Decreases in routine healthcare practices have been shown to occur during disasters. However, research regarding the impacts of natural disasters, pandemics, or military conflicts on emergency medical services (EMS) is scarce.

Objectives: This study assessed the impact of a military conflict versus the coronavirus disease 2019 (COVID-19) pandemic on a national EMS organization in terms of responses to overall daily emergencies, medical illnesses, motor vehicle collisions, and other injuries.

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Article Synopsis
  • - The study investigates how a pandemic affects Emergency Medical Services (EMS) by analyzing ambulance calls in Israel during early 2020, specifically related to COVID-19 symptoms.
  • - Results showed an increase in calls for COVID-19-related symptoms, while calls for other medical issues, like cardiovascular problems and injuries, decreased during the same time.
  • - This information could help EMS improve their preparedness and better address public health needs during future epidemics or pandemics.
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Purpose: The aim of the present study was to investigate if wheel running exercise could offset the detrimental influences of independent or combined high-phosphorus and low-calcium diets on bone tissue in rats.

Methods: Forty male dark Agouti rats were randomly assigned to eight groups of five animals. Four sedentary groups (SED) and four voluntary trained groups (TR) were fed over 6 wk of either a standard food or a modified diet, namely, high phosphorus (HP), low calcium (LCa), or high phosphorus combined with low calcium (HP/LCa).

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During spaceflights in the shuttle, rats are provided specific food bars. To determine whether this diet allows normal body and skeletal growth, we used four groups of rats fed either standard pellet food or space food bars during a 2-wk unloading experiment. We recorded food intake, body weight, tibial bone mass, and mineral content by ash analyses, cancellous bone volume, and cell activities by histomorphometry.

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Using analyses of iliac crest cell and tissue, back-scattered electron imaging, and biochemical techniques, we characterized the effects of a 14-day spaceflight (Bion 11) on bone structure and bone formation in two 3- to 4-yr-old male rhesus monkeys compared with eight age-matched Earth-control monkeys. We found that postflight bone volume was 35% lower than preflight values in flight monkeys. This was associated with reduced osteoid (-40%) and mineralizing (-32%) surfaces and decreased bone formation rate (-53%).

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Skeletal unloading induced by hindlimb suspension in rats reduces bone formation and induces osteopenia, but its effect on adipogenesis is unknown. We assessed the effects of unloading and transforming growth factor (TGF) beta2 on bone marrow stromal cell adipocyte differentiation in relation with osteoblast differentiation. Skeletal unloading rapidly (4-7 days) decreased osteoblast transcription factor Runx2, osteocalcin (OC), and type I collagen messenger RNA (mRNA) levels and reduced bone formation in the long bone metaphysis.

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