Treatment of unicentric Castleman disease with neoadjuvant rituximab.

Angiofollicular lymph node hyperplasia, known more commonly as Castleman disease, is a rare lymphoproliferative disorder. Castleman disease has two distinct clinical manifestations described as unicentric and multicentric disease. These presentations have distinct treatment algorithms and portend very different prognoses.

Does the diagnosis of coronary calcification with electron beam computed tomography motivate behavioral change in smokers?

Background: Electron beam computed tomography is promoted as a test that may enhance patient motivation to alter cardiovascular risk behaviors.

Methods: We surveyed a consecutive sample of asymptomatic, active smokers (N = 144) who underwent screening electron beam computed tomography about their current motivation to alter their smoking behavior in the context of their tomography results.

Results: Patients with coronary artery calcification (42% of the sample) were more likely to perceive increased cardiovascular risk (42 vs.