A metamaterial-enabled design enhancing decades-old short backfire antenna technology for space applications.

Nearly two decades of intense study have passed since the term metamaterials was first introduced in 1999. In spite of their great promise, however, metamaterials have been slow to find their way into practical devices, and examples of real-world applications remain rare. In this paper, an Advanced Short Backfire Antenna (A-SBFA), augmented with anisotropic metamaterial surfaces (metasurfaces), has been designed to achieve a very high aperture efficiency across two frequency bands.

Association of Amyloid Positron Emission Tomography With Changes in Diagnosis and Patient Treatment in an Unselected Memory Clinic Cohort: The ABIDE Project.

Importance: Previous studies have evaluated the diagnostic effect of amyloid positron emission tomography (PET) in selected research cohorts. However, these research populations do not reflect daily practice, thus hampering clinical implementation of amyloid imaging.

Objective: To evaluate the association of amyloid PET with changes in diagnosis, diagnostic confidence, treatment, and patients' experiences in an unselected memory clinic cohort.

Alzheimer's biomarkers in daily practice (ABIDE) project: Rationale and design.

Introduction: The Alzheimer's biomarkers in daily practice (ABIDE) project is designed to translate knowledge on diagnostic tests (magnetic resonance imaging [MRI], cerebrospinal fluid [CSF], and amyloid positron emission tomography [PET]) to daily clinical practice with a focus on mild cognitive impairment (MCI).

Methods: ABIDE is a 3-year project with a multifaceted design and is structured into interconnected substudies using both quantitative and qualitative research methods.

Results: Based on retrospective data, we develop personalized risk estimates for MCI patients.

Radioisotopic Purity of Sodium Pertechnetate 99mTc Produced with a Medium-Energy Cyclotron: Implications for Internal Radiation Dose, Image Quality, and Release Specifications.

Unlabelled: Cyclotron production of 99mTc is a promising route to supply 99mTc radiopharmaceuticals. Higher 99mTc yields can be obtained with medium-energy cyclotrons in comparison to those dedicated to PET isotope production. To take advantage of this capability, evaluation of the radioisotopic purity of 99mTc produced at medium energy (20-24 MeV) and its impact on image quality and dosimetry was required.

Assessment of radionuclidic impurities in cyclotron produced (99m)Tc.

Introduction: The commercial viability of cyclotron-produced (99m)Tc as an alternative to generator-produced (99m)Tc depends on several factors. These include: production yield, ease of target processing and recycling of (100)Mo, radiochemical purity, specific activity as well as the presence of other radionuclides, particularly various Tc radioisotopes that cannot be separated chemically and will remain in the final clinical preparation. These Tc radionuclidic impurities are derived from nuclear interactions of the accelerated protons with other stable Mo isotopes present in the enriched (100)Mo target.

An octave-bandwidth negligible-loss radiofrequency metamaterial.

Metamaterials provide an unprecedented ability to manipulate electromagnetic waves and are an enabling technology for new devices ranging from flat lenses that focus light beyond the diffraction limit to coatings capable of cloaking an object. Nevertheless, narrow bandwidths and high intrinsic losses arising from the resonant properties of metamaterials have raised doubts about their usefulness. New design approaches seek to turn the perceived disadvantages of dispersion into assets that enhance a device's performance.