Consequences of the addition of nitrous oxide to anesthesia during pneumoperitoneum in videolaparoscopic surgeries.

Background And Objectives: The use of pneumoperitoneum during videolaparoscopic surgeries activates neuroendocrine mechanisms, and causes cardiovascular and hormonal changes. The aim of this study was to evaluate the effects of the addition of nitrous oxide, to maintain adequate anesthetic levels, on the cardiovascular sympathetic response and in the expired concentration of sevoflurane (ECsevo) during pneumoperitoneum, by evaluating hemodynamic parameters, BIS, and SEF95%, during videolaparoscopic cholecystectomies.

Methods: Thirty-one patients, physical status ASA I and II, ages 19 to 76 years, were included in the study.