C-reactive protein as a predictor of chorioamnionitis.

Context: Chorioamnionitis (CAM) affects many pregnancies complicated by preterm premature rupture of membranes (PPROM). Finding a serum factor that could accurately predict the presence of CAM could potentially lead to more efficient management of PPROM and improved neonatal outcomes.

Objective: To determine if C-reactive protein (CRP) is an effective early marker of CAM in patients with PPROM.