Publications by authors named "Erik J L Mannaert"
J Clin Psychiatry
August 2008
Article Synopsis
- Long-acting risperidone, given intramuscularly once a month, was studied to understand its effect on D(2) dopamine receptor binding in patients with schizophrenia.
- Seven patients received monthly injections and underwent PET scans to measure D(2) binding shortly before their next dose.
- Results showed that even with variable D(2) receptor occupancy levels, some patients maintained stability without relapse, suggesting that high D(2) occupancy might not be essential for ongoing treatment effectiveness.
