Intestinal inflammatory profile shows increase in a diversity of biomarkers in irritable bowel syndrome.

It has been proposed that irritable bowel syndrome (IBS) is a low-grade mucosal inflammatory disease. To characterize the intestinal inflammatory profile in IBS patients with or without fructose intolerance. Patients referred to colonoscopy with IBS complaints were screened for participation.

Self-reported dietary fructose intolerance in irritable bowel syndrome: Proposed diagnostic criteria.

Aim: To study the criteria for self-reported dietary fructose intolerance (DFI) and to evaluate subjective global assessment (SGA) as outcome measure.

Methods: Irritable bowel syndrome (IBS) patients were randomized in an open study design with a 2 wk run-in on a habitual IBS diet, followed by 12 wk with/without additional fructose-reduced diet (FRD). Daily registrations of stool frequency and consistency, and symptoms on a visual analog scale (VAS) were performed during the first 4 wk.

Effect of fructose-reduced diet in patients with irritable bowel syndrome, and its correlation to a standard fructose breath test.

Objectives: To perform a validation of dairy registrations for use as diagnostic tool in IBS and fructose malabsorption (FM). To investigate the precision of the fructose breath test (FBT) as compared with symptom score reduction on fructose-reduced diet (FRD) in a cohort of patients with Rome II defined irritable bowel syndrome (IBS).

Design: IBS patients diagnosed according to the Rome II criteria and with no organic gastrointestinal disease were enrolled.