Publications by authors named "Erick de la Torre"
A supercritical fluid chromatography-based targeted purification procedure using tandem mass spectrometry and molecular networking was developed to analyze, annotate, and isolate secondary metabolites from complex plant extract mixture. This approach was applied for the targeted isolation of new antiviral diterpene esters from Euphorbia semiperfoliata whole plant extract. The analysis of bioactive fractions revealed that unknown diterpene esters, including jatrophane esters and phorbol esters, were present in the samples.
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- The rise of antibiotic-resistant bacteria is a serious global health issue, prompting research into alternative treatments.
- The study found that sub-lethal concentrations of tellurite significantly enhance the effectiveness of various antibiotics against both gram-negative and gram-positive bacteria.
- Particularly effective combinations include tellurite with cefotaxime and other antibiotics that disrupt cell walls or protein synthesis, suggesting that tellurite could be a valuable adjuvant in treating multi-resistant infections.