In vivo sensing of rabbit cornea by terahertz technology.

A Novel scalable approach using Terahertz (THz) waves together with the electromagnetic field simulation was applied to investigate four rabbits of eight rabbit corneas in vivo. One eye of each rabbits' corneas was edema induced; the other eye of the corneas served as the control. The simulation revealed the propagation of THz waves at a certain distance along the sub-surface of the cornea.

Terahertz spectroscopy analysis of human corneal sublayers.

Significance: Corneal diseases is a major cause of reversible blindness in the world. Monitoring the progression of human corneal edema or corneal scarring to prevent the disease entering into the end stage is crucial.

Aim: We present a method for sensing human corneal composition at different depths, namely focused on the epithelium and stromal layer, using high-sensitivity terahertz (THz) broadband spectroscopy.

Ex vivo sensing and imaging of corneal scar tissues using terahertz time domain spectroscopy.

Pulsed terahertz (THz) broadband spectroscopy and imaging were applied to investigate ex vivo rabbit corneal scar tissues. Scars with different depths and densities were created by laser ablation on four corneal samples while two corneal samples untouched were used as control. The THz time-domain spectroscopy and reconstructed images illustrated the scar tissue density and gave out depth variation distribution profiles.