Publications by authors named "Erica Patricia Pereira"
A.C. Smith is an endemic tree from Northeastern Brazil used in folk medicine as teas, decocts and syrups for the treatment of various respiratory and inflammatory diseases, since therapeutic properties have been attributed to compounds from its stem bark and seeds.
View Article and Find Full Text PDFLupeol inhibits LPS-induced neuroinflammation in cerebellar cultures and induces neuroprotection associated to the modulation of astrocyte response and expression of neurotrophic and inflammatory factors.
Markley Silva Oliveira-Junior Erica Patricia Pereira Vanessa Cristina Meira de Amorim Luã Tainã Costa Reis Ravena Pereira do Nascimento
Int Immunopharmacol
May 2019
Article Synopsis
- Neuroinflammation in the central nervous system, primarily involving astrocytes and microglia, contributes to neuron damage in neurodegenerative disorders like Parkinson's and Alzheimer's disease.
- A study on lupeol, a dietary triterpene with antioxidant properties, found that it provided neuroprotective effects in cerebellar cultures treated with inflammatory agents.
- Lupeol not only changed the morphology of astrocytes to a protective form but also down-regulated pro-inflammatory markers and up-regulated neurotrophic factors, highlighting its potential for mitigating neuroinflammation and promoting neuron health.