Publications by authors named "Eric de la Roche"

Article Synopsis
  • A case study of a 41-year-old man showed successful surgical resection of pleural implants related to his previous atypical meningioma, which included innovative techniques like intrathoracic hyperthermic chemotherapy.
  • The patient had an uneventful recovery and has been free of pleural recurrence for 12 months, indicating that this combined surgical approach could be a safe option for treating pleural metastases from meningiomas, though further research is needed to confirm its effectiveness.
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Objectives: Only a few case reports and small case series of patients with sarcoidosis or sarcoid-like reaction and testicular germ cell tumors (GCT) have been reported in the literature. We performed a retrospective study of patients with testicular GCT managed at the Centre Léon-Bérard, who presented granulomatosis.

Methods: We performed a computerized search to identify all male patients with both a diagnosis of sarcoidosis or granuloma and testicular tumors seen at the Centre Léon-Bérard between 1992 and 2008.

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Spontaneous pneumothorax may be one of the presenting manifestation of metastatic epithelioid sarcoma even if imaging does not show evident metastatic nodules. We report the case of a 24-year-old man presenting a bilateral spontaneous pneumothorax in association with an epithelioid sarcoma developed in the right foot. CT-scan revealed bilateral microcystic lesions with no evidence of metastatic disease.

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  • The study analyzed the outcomes of 228 patients who underwent pneumonectomy following induction chemotherapy for non-small cell lung cancer, noting concerns over high mortality rates associated with this procedure.
  • Postoperative morbidity was reported at 37%, with significant risks including chronic obstructive pulmonary disease and extended surgical factors, while 30-day mortality was 5.3% and 90-day mortality was 9.2%.
  • Overall survival rates demonstrated 68% at 1 year, 39% at 3 years, and 32% at 5 years, concluding that induction chemotherapy did not negatively impact outcomes and pneumonectomy can be deemed reasonable for experienced surgeons.
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  • Serous cystadenomas (SCAs) are benign pancreatic tumors that are often treated conservatively when asymptomatic, especially if they are located in the pancreas head or if there are multiple lesions throughout the pancreas.* -
  • Accurate diagnosis of SCAs is crucial, relying on specific radiological and biological features to differentiate them from other types of pancreatic tumors, particularly mucinous ones.* -
  • A case study presented involves a patient with large (over 10 cm), multiple asymptomatic SCAs who has been monitored for 3 years without any symptoms or significant changes in the tumors, with imaging confirming their benign characteristics.*
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  • Complete cyst excision with biliary reconstruction is the preferred treatment for patients with congenital bile duct cysts (BDC), but it becomes complicated when the cyst extends to the main biliary convergence (MBC).
  • A multicenter study analyzed 49 adult patients with type I and IV BDC, finding that 14% had cysts affecting the MBC, with similar clinical presentations and outcomes compared to those without MBC involvement.
  • The study revealed a high rate of incomplete proximal cyst excision (86%) in the MBC involvement group and indicated a significantly increased risk of subsequent cancer (29%) in these patients, suggesting the need for further research on this issue.
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  • Primary lung tumors resembling salivary gland neoplasms are rare, and there's limited research on their immunohistochemical characteristics.
  • The report details two cases of bronchial pleomorphic and mucous gland adenomas, highlighting their unique structures and the presence of specific cellular components.
  • Both tumors exhibited strong staining for high molecular weight keratins while lacking TTF-1 expression, which aids in identifying these benign tumors and differentiating them from adenocarcinomas in biopsy samples.
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The aim of this study was to identify and to classify anatomical hepatic artery (HA) variations concerning 932 HA dissections in liver transplantation (LT). Normal HA distribution was found in 68.1%.

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Article Synopsis
  • * A study of 46 patients using this approach showed no postoperative deaths, low rates of complications, and a median follow-up of 50 months, demonstrating an 8.5% local recurrence rate and a 72% survival rate at five years.
  • * The strategy emphasizes rigorous pre- and post-operative evaluation for factors like quality of life, sexual and urinary well-being, which are crucial for successful outcomes, particularly for patients with T2 and T3 tumors near the anal canal.
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  • - The study assessed the feasibility, safety, and outcomes of laparoscopic pancreatic resections in 15 patients with different types of pancreatic conditions.
  • - Out of the 15 patients, 10 successfully underwent the laparoscopic procedure, facing complications like pancreatic fistula (20%) and peripancreatic collection (13%).
  • - The findings suggest that while laparoscopic pancreatic resection is possible for tumors, managing the pancreatic stump is crucial for improving patient outcomes.
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  • The study investigates how antireflux surgery affects patients with columnar-lined esophagus (CLE) who do not have high-grade dysplasia, using data from 26 patients.
  • Among patients with intestinal metaplasia, a significant number experienced regression, and none progressed to more severe dysplasia or cancer over long-term follow-up.
  • The findings suggest that antireflux surgery may stabilize CLE, and while complete regression can occur, it is not consistent across all patients.
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  • A 64-year-old man had lung cancer that had spread to the lower left lobe of his lung.
  • After trying chemotherapy with partial success, surgery options like wedge resection and lobectomy were not viable due to his lung function.
  • Instead, doctors used radiofrequency ablation to target the metastasis, leading to a unique delayed cavitation without signs of infection.
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