Publications by authors named "Eric W Lai"

Objective: To compare the sensitivity of 3 groups of masked graders with varying levels of ophthalmic training to identify peripheral retinal breaks utilizing ultra-widefield orthogonal, directed peripheral steering, and auto-montaged images.

Design: Retrospective observational cohort study.

Participants: 155 patients from a single vitreoretinal specialist's practice.

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Autoimmune thyroid diseases (ATDs) are potentially connected to lacrimal gland dysfunction and ocular surface disruption. This study aimed to evaluate the relationships between ATD, dry eye disease (DED), and corneal surface damage. In a matched nationwide cohort study, we used Taiwan's National Health Insurance research database to compare the incidences of DED and corneal surface damage between subjects with and without ATD.

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Blood cells trapped in stasis have been reported within the microcirculation, but their relevance to health and disease has not been established. In this study, we introduce an imaging approach that reveals the presence of a previously-unknown pool of erythrocytes in stasis, located within capillary segments of the CNS, and present in 100% of subjects imaged. These results provide a key insight that blood cells pause as they travel through the choroidal microvasculature, a vascular structure that boasts the highest blood flow of any tissue in the body.

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Article Synopsis
  • * Comprehensive examinations revealed low serum vitamin A levels, and after vitamin A supplementation, the patient showed improved vision and closure of the macular hole within two months.
  • * The report emphasizes the importance of considering vitamin A deficiency as a potential cause for specific eye conditions when other common causes have been excluded.
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