Publications by authors named "Eric Victor van Leen"
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Synopsis of recent research by authors named "Eric Victor van Leen"
- Eric Victor van Leen's research primarily focuses on the mechanics of oriented cell divisions in epithelial tissues, particularly how forces and cellular shapes influence these processes.
- His 2020 article highlights the role of the canonical pathway involving NuMA and dynein in mitotic spindle orientation, which is critical for asymmetric cell divisions and overall tissue integrity.
- Van Leen's findings suggest that NuMA not only participates in the recruitment of necessary factors but also plays a direct role in force generation during cell division, thereby influencing the anisotropy of cellular tensions and shapes.