Screening for trisomy 21 in Flanders: a 10 years review of 40.490 pregnancies screened by maternal serum.

Objective: To evaluate maternal serum screening for trisomy 21 (MSS) in Flanders between 1992 and 2002.

Study Design: Data of a large database on the results of MSS, nuchal translucency (NT) and pregnancy outcome were analysed retrospectively.

Results: Despite an excellent performance of second trimester MSS at a maternal age > or = 35 years (94.

Endocrine and metabolic effects of growth hormone (GH) compared with GH-releasing peptide, thyrotropin-releasing hormone, and insulin infusion in a rabbit model of prolonged critical illness.

Treatment with recombinant human GH (rhGH) increases the mortality of critical illness. We postulated that combined GH-releasing peptide-2 (GHRP-2), TRH, and insulin infusion is a less toxic anabolic strategy through a putative inability to overstimulate the GH axis and a capacity to normalize thyroid hormone concentrations while foregoing excessive hyperglycemia. Burn-injured, parenterally fed, New Zealand White rabbits were randomized to receive 4-d treatment with saline (n=8); 60 microg/kg.