Publications by authors named "Eric Senabre Marchan"
Mol Psychiatry
February 2022
Article Synopsis
- The study examines how drug addiction, particularly to cocaine, may be influenced by changes in gene expression regulated by micro-RNAs (miRNAs), focusing on their role in specific brain regions involved in addiction.
- Researchers found that certain miRNAs were elevated in the nucleus accumbens (NAc) of mice after prolonged cocaine use, with a particular emphasis on miR-1 due to its impact on key genes like Fosb and Npas4 that are involved in addiction responses.
- Through experiments that overexpressed miR-1 in different types of striatal neurons, the study revealed contrasting effects on cocaine-seeking behavior, suggesting that miR-1 plays a specific and important role in modulating addiction behaviors depending
