Publications by authors named "Eric S Storey"
Background: Inherited primary open-angle glaucoma (POAG) in Beagle dogs is a well-established large animal model of glaucoma and is caused by a G661R missense mutation in the gene. Using this model, the study describes early clinical disease markers for canine glaucoma.
Methods: Spectral-domain optical coherence tomography (SD-OCT) was used to assess nine adult, -mutant (median age 45.
Canine glaucoma is a group of disorders that are generally associated with increased intraocular pressure (IOP) resulting in a characteristic optic neuropathy. Glaucoma is a leading cause of irreversible vision loss in dogs and may be either primary or secondary. Despite the growing spectrum of medical and surgical therapies, there is no cure, and many affected dogs go blind.
View Article and Find Full Text PDFSurvey of cytokines in normal canine tears by multiplex analysis: A pilot study.
Vet Immunol Immunopathol
July 2018
Objectives: The purpose of this pilot study was to use a multiplexed assay to measure cytokines in normal stimulated canine tears.
Methods: 25 healthy dogs were included in the study. Stimulated tears were collected in capillary tubes from the right (OD) and left (OS) eyes and stored at -80 °C until batch sample analysis was performed.
A 3-year-old neutered male boxer dog presented with a 6-month history of a waxing and waning mass of the left dorsotemporal eyelid margin. Cytology and biopsy confirmed a diagnosis of mast cell neoplasia. Systemic staging of the dog failed to reveal any evidence of metastatic neoplasia.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to assess tear production in Hispaniolan Amazon parrots using the phenol red thread test (PRTT) and Schirmer tear test (STT) before and after applying an anesthetic.
- During the tests, 24 parrots underwent a thorough eye examination over four weeks, measuring PRTT and STT both with and without anesthetic.
- Results showed that while the PRTT values remained consistent, the STT values dropped significantly with anesthesia, highlighting the effectiveness of both tests but pointing to differences in how anesthesia impacts measurements.
Intraocular choristomas are rare anomalies in domestic animals and are often associated with multiple ocular malformations. A Thoroughbred foal presented for ocular abnormalities and was diagnosed with microphthalmia, corneal dermoids, severe anterior segment dysgenesis (including glandular choristomas), aphakia, retinal dysplasia, and optic nerve hypoplasia. Morphological, histochemical, and immunohistochemical comparisons were made between ocular choristomatous tissues from this foal and lacrimal gland, third eyelid gland, nasopharynx, trachea, and lacrimal sac/nasolacrimal duct from normal horses.
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- The study aimed to assess the prevalence and characteristics of Borzoi chorioretinopathy in western Canada, focusing on lesion progression and potential hereditary connections.
- A total of 103 Borzoi dogs were examined, revealing 12 affected dogs with non-progressive lesions over five years; retinal function appeared normal compared to unaffected dogs and no clear inheritance pattern was identified.
- The findings indicate that Borzoi chorioretinopathy is likely an acquired condition characterized by specific retinal changes, with ongoing research needed to further understand its etiology and inheritance.
Article Synopsis
- A solid grasp of tear film physiology and associated abnormalities is crucial for veterinarians to effectively diagnose and treat issues related to tear production, whether it's a lack of quantity or quality in the tear film.
- The article covers the development, structure, and functions of various glands involved in tear production, including lacrimal and tarsal glands, as well as goblet cells.
- It also discusses specific treatments for tear film deficiencies, such as lacrimostimulants like cyclosporine and lacrimomimetics, which serve as artificial tear replacements.
The objectives of this study were to define the clinical syndrome of retinal dysplasia and persistent primary vitreous in Miniature Schnauzer dogs and determine the etiology. We examined 106 Miniature Schnauzers using a biomicroscope and indirect ophthalmoscope. The anterior and posterior segments of affected dogs were photographed.
View Article and Find Full Text PDFObjective: To determine survival over time of infectious equine herpesvirus-4, feline herpesvirus-1, and feline calicivirus in three commercially available and commonly used ophthalmic solutions (eyewash, fluorescein, and proparacaine HCl).
Sample Population: Viruses used in this study were originally isolated from eyes of animals referred to the University of Illinois. Equine herpesvirus-4 was propagated in MDBK cells and feline herpesvirus-1 and feline calicivirus in CRFK cells.