Publications by authors named "Eric R Holz"
Purpose: To investigate late retinal findings and complications of eyes with a history of retinopathy of prematurity (ROP) that did not meet treatment criteria and did not receive treatment during infancy.
Design: Retrospective, nonconsecutive, noncomparative, multicenter case series.
Participants: Three hundred sixty-three eyes of 186 patients.
Purpose: To describe the multimodal imaging findings, including optical coherence tomography angiography analysis, and spectrum of etiologies associated with Amalric triangular choroidal infarction.
Methods: This study is a multicenter, retrospective, observational case series review of the clinical and multimodal imaging findings for six patients with Amalric triangular choroidal infarction.
Results: Six patients (10 eyes) with Amalric triangular choroidal infarction were enrolled.
Aim: To describe the long-term outcomes of lens-sparing vitrectomy (LSV) for retinopathy of prematurity (ROP).
Methods: Single-centre retrospective case series of eyes that underwent LSV for ROP between 1998 and 2005 and had a follow-up of at least 5 years. The primary outcome was the mean visual acuity, and secondary outcomes were the proportion of eyes without functional vision, proportion of eyes with anatomic success, proportion of Stage 4A eyes with vision better than 20/400, proportion of Stage 4B eyes with vision better than 20/800.
Purpose: To describe a case of exudative macular detachment secondary to peripheral exudative chorioretinopathy with a favorable anatomic and visual outcome following treatment with intravitreal bevacizumab.
Methods: The medical records of a patient with peripheral exudative chorioretinopathy were reviewed.
Results: Macular reattachment was achieved with a corresponding visual acuity improvement that was maintained over an uncomplicated 17-month clinical course.
Long-term observation of exposed scleral exoplant without topical antibiotic prophylaxis.
Retin Cases Brief Rep
November 2014
Purpose: The purpose of this study was to describe a case of long-term observation without topical antibiotic prophylaxis for asymptomatic scleral exoplant exposure.
Methods: The medical records of a patient with long-term observation for asymptomatic scleral exoplant exposure were reviewed.
Results: No complications or clinical changes were noted throughout a 36-month course of observation for exoplant exposurei.
Objective: To evaluate the refractive outcomes of 3-port lens-sparing vitrectomy (LSV) for subtotal retinal detachments owing to retinopathy of prematurity.
Methods: The study included 9 infants who had undergone complete ablative laser treatment for threshold retinopathy of prematurity in both eyes, subsequently developed stage 4A retinal detachment in 1 eye for which they underwent LSV, and maintained complete retinal attachment bilaterally. Eyes that underwent LSV were compared with fellow eyes.
Evaluating retinal toxicity of intravitreal caspofungin in the mouse eye.
Invest Ophthalmol Vis Sci
November 2010
Purpose: Caspofungin is a synthetic echinocandin antifungal agent that inhibits the synthesis of β(1,3)-D-glucan, an essential component of the cell wall of susceptible Aspergillus and Candida species. In this study, retinal toxicity was determined after intravitreal injection of caspofungin in a mouse model to assess its safety profile for the treatment of fungal endophthalmitis.
Methods: Caspofungin acetate was injected intravitreally in the left eyes of male C57BL/6 mice, with final vitreal concentrations corresponding to 0.
Refractive outcomes of three-port lens-sparing vitrectomy for retinopathy of prematurity (An AOS Thesis).
Trans Am Ophthalmol Soc
December 2009
Purpose: To study the refractive outcomes of 3-port lens-sparing vitrectomy (LSV) for subtotal retinal detachments due to retinopathy of prematurity (ROP). Lens-sparing vitrectomy may provide superior refractive outcomes by limiting induced myopia of prematurity.
Methods: This is a retrospective, consecutive, nonrandomized, comparative (paired eye) study.
Purpose: To report on the outcomes of 25-gauge pars plana vitrectomy using sulfur hexafluoride and no prone positioning for repair of macular holes.
Methods: Retrospective case series of 44 consecutive patients who underwent pars plana vitrectomy with internal limiting membrane peeling for repair of stages 2 to 4 idiopathic macular holes using 20% to 30% sulfur hexafluoride. No postoperative prone positioning or gas augmentation was used.
Background: Panuveitis and chorioretinitis in infants with Langerhans cell histiocytosis are rare and fundus photographic documentation is lacking in the literature.
Methods: Case report with fundus photography.
Results: The authors report a case of an infant with disseminated Langerhans cell histiocytosis who presented with panuveitis in the right eye and chorioretinitis in left eye.
Bacillus cereus endophthalmitis following intravitreous bevacizumab injection.
Ophthalmic Surg Lasers Imaging
April 2008
The first case of Bacillus cereus endophthalmitis following an intravitreous injection of bevacizumab is described. A 77-year-old man presented to a retina specialist with an active choroidal neovascularization related to age-related macular degeneration for which he received intravitreous bevacizumab (1.25 mg) and post-injection topical gatifloxacin.
View Article and Find Full Text PDFPurpose: To compare outcomes and complications of pars plana lensectomy-vitrectomy (PPL-PPV) for the management of ectopia lentis in children with and without a foldable iris-sutured intraocular lens (IOL).
Setting: Department of Ophthalmology, Baylor College of Medicine, Houston, Texas, USA.
Methods: This study comprised 22 eyes of 12 consecutive pediatric patients with ectopia lentis who had PPL-PPV by the same vitreoretinal surgeon with (12 eyes; Group L) or without (10 eyes; Group A) insertion of a foldable iris-sutured IOL between June 1998 and October 2006.
Purpose: The aim of this study was to evaluate whether intravitreal triamcinolone hexacetonide (TH) is a safe, longer lasting alternative to intravitreal triamcinolone acetonide (TA) in the rabbit eye.
Methods: Three groups, each comprising of 15 Dutch-belted rabbits, received a unilateral injection of 0.1 mL of drug and 0.
Purpose: To report the outcome of repeated photodynamic therapy (PDT) for a patient with choroidal neovascularization complicating Stargardt disease.
Methods: Interventional case report.
Results: A 41-year-old patient with Stargardt disease developed unilateral choroidal neovascularization treated multiple times with PDT over 2.
Background: There is controversy on whether etanercept, an anti-tissue necrosis factor agent, shares infliximab's purported efficacy in the treatment of intermediate uveitis and, in particular, intermediate uveitis-associated cystoid macular edema.
Methods: Interventional case report.
Results: A 29-year-old patient with decreased vision bilaterally secondary to cystoid macular edema complicating chronic idiopathic intermediate uveitis refractory to oral corticosteroids, methotrexate (17.
Purpose: To establish the necessity for an early follow-up examination after an initial funduscopic examination with negative results for patients with acute, symptomatic posterior vitreous detachment (PVD).
Design: Retrospective case-control study and meta-analysis.
Methods: Records were reviewed of patients seeking treatment over a 4.
Purpose: To investigate whether intravitreal Kenalog (IVTK; Bristol Meyers Squibb Company, Princeton, NJ) produces histologic or electroretinographic changes in the rabbit retina up to 3 months after injection.
Methods: Ten Dutch-belted rabbits were injected with 4 mg/0.1 mL Kenalog in one eye and 0.
Purpose: To study the clearance of a single dose of intravitreally injected moxifloxacin in rabbits.
Methods: Intravitreal injections of 200 microg/0.1 mL of moxifloxacin were performed in rabbits.
Purpose: To determine the anatomical success rate of lensectomy and vitrectomy with and without intravitreal triamcinolone acetonide (TA) for vascularly active stage 5 tractional retinal detachments due to retinopathy of prematurity (ROP).
Methods: In a retrospective, interventional, single-surgeon, consecutive case series, the records of 21 eyes of 21 patients presenting with stage 5 retinal detachment secondary to ROP who underwent primary pars plicata vitrectomy with lensectomy from February 1998 to January 2004 were evaluated. All eyes were vascularly active at the time of surgery.
Purpose: To assess the anatomical success rate after three-port lens-sparing vitrectomy (LSV) in stage 5 (total) retinal detachments secondary to retinopathy of prematurity.
Methods: In a retrospective, interventional, single-surgeon, consecutive case series, the records of 33 eyes of 21 patients presenting with stage 5 retinal detachment secondary to retinopathy of prematurity who underwent primary three-port LSV from February 1998 to January 2004 were evaluated. Twenty-one eyes (63.
Objective: To assess the visual acuity of eyes successfully treated with 3-port lens-sparing vitrectomy for stage 4 retinopathy of prematurity.
Methods: Of 102 consecutive eyes achieving at least posterior pole reattachment, 30 eyes of 26 patients were tested by Teller or Allen acuity measurements and were subsequently converted to logarithm of the minimum angle of resolution (logMAR). Visual outcomes were also examined as either favorable or unfavorable (Snellen equivalent >20/200).