Publications by authors named "Eric Porterfield"
Background: A nonroutine event is any aspect of clinical care perceived by clinicians or trained observers as a deviation from optimal care based on the context of the clinical situation. The authors sought to delineate the incidence and nature of intraoperative nonroutine events during anesthesia care.
Methods: The authors prospectively collected audio, video, and relevant clinical information on 556 cases at three academic hospitals from 1998 to 2004.
Article Synopsis
- Anesthesia providers often engage in non-patient care distractions, especially when workloads are light, but the impact on patient care was previously unclear.
- A study observed 319 cases and found that 54% included self-initiated distractions, primarily personal internet use, lasting an average of 2.3 seconds during maintenance periods.
- Although distractions were common, they generally did not result in adverse events, indicating that anesthesia staff can manage their nonclinical activities effectively; future efforts should aim to minimize more significant distractions.
Objectives: A nonroutine event (NRE) is defined as any event that deviates from ideal clinical care for a given patient in a specific clinical situation. We sought to compare anesthesia providers' reporting of NREs with the incidence of significant physiological disturbances (SPDs) detected via retrospective videotape review. SPD criteria were defined prestudy to be deviations of physiological parameters (heart rate, systolic blood pressure, and oxygen saturation) requiring clinical intervention.
View Article and Find Full Text PDFPurpose: AAV vectors produce stable transgene expression and elicit low immune response in many tissues. AAVs have been the vectors of choice for gene therapy for the eye, in particular the retina. scAAVs are modified AAVs that bypass the required second-strand DNA synthesis to achieve transcription of the transgene.
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