"At Least We Could Give Our Input": Underrepresented Student Narratives on Conventional and Guided Inquiry-Based Laboratory Approaches.

Policy documents continually stress the need to develop a scientifically literate and diverse workforce. One commonly recommended way to achieve these goals is through the redesign of introductory level science courses to foster students' interest in science. Such redesigns take advantage of a myriad of evidence-based strategies such as inquiry and context-based approaches that place students at the center of learning.

PCR inhibitor removal using the NucleoSpin® DNA Clean-Up XS kit.

Forensic evidence samples are collected from an unlimited variety of substrates, which may contain compounds known to inhibit the polymerase chain reaction (PCR). These PCR inhibitors are co-extracted with the DNA sample and can negatively affect the DNA typing results, which can range from partial to complete inhibition of the short tandem repeat (STR) PCR. One potential solution is to remove the PCR inhibitors from the extracts prior to the STR PCR with the NucleoSpin(®) DNA Clean-Up XS kit.

Capillary electrophoretic analysis of phosphorus species in clandestine methamphetamine laboratory samples.

The clandestine manufacture of methamphetamine is a spreading epidemic. Manufacturing methods are constantly changing, necessitating the implementation of new analytical tools to identify materials from these labs. Characterization of phosphate, phosphite, and hypophosphite ions is necessary to distinguish the various phosphorus-iodine manufacturing methods that are popular methods for reducing pseudoephedrine to methamphetamine.

Structural determination of the principal byproduct of the lithium-ammonia reduction method of methamphetamine manufacture.

One common method of illicit methamphetamine manufacture utilizes an alkali metal, typically lithium, and liquid ammonia to chemically reduce ephedrine or pseudoephedrine to form methamphetamine. This method is often referred to as the lithium-ammonia reduction method or the Birch reduction method. While the hydroxyl group of ephedrine is more reactive than the aromatic ring, excess alkali metal and the presence of a proton source allow the formation of a cyclohexadiene byproduct not found in samples of methamphetamine produced from other manufacturing methods.