Publications by authors named "Eric P Chow"

Background: Despite mounting evidence showing that kissing (tongue-kissing) may transmit gonorrhoea between men who have sex with men (MSM), little data exists on factors influencing the duration of kissing while they are above and/or lying underneath a partner for this population group.

Methods: Between May 2019 and March 2020, we invited MSM aged ≥18 years who attended the Melbourne Sexual Health Centre (MSHC) to participate in a survey about the duration of their kissing (minutes) and intimate position while kissing (i.e.

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Objective: Awareness of one's individual risk of sexually transmitted infections (STIs) and human immunodeficiency virus (HIV) is a necessary precursor to engagement with prevention strategies and sexual health care. Web-based sexual health applications may improve engagement in sexual health prevention and care by providing individualised and evidence-based sexual health information. The STARTOnline () study sought the views of sexual health service users on three web-based sexual health applications to better understand their usefulness, acceptability and accessibility.

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Objective: HIV pre-exposure prophylaxis (PrEP) became available in Victoria, Australia, in 2016. We examined non-occupational post-exposure prophylaxis (nPEP) usage among gay, bisexual and other men who have sex with men (MSM) before and after PrEP became available.

Methods: We included MSM attending Melbourne Sexual Health Centre for nPEP between 2011 and 2021.

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Background: Current clinical care for common bacterial STIs (Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG) and Mycoplasma genitalium (MG)) involves empiric antimicrobial therapy when clients are symptomatic, or if asymptomatic, waiting for laboratory testing and recall if indicated. Near-to-patient testing (NPT) can improve pathogen-specific prescribing and reduce unnecessary or inappropriate antibiotic use in treating sexually transmitted infections (STI) by providing same-day delivery of results and treatment.

Methods: We compared the economic cost of NPT to current clinic practice for managing clients with suspected proctitis, non-gonococcal urethritis (NGU), or as an STI contact, from a health provider's perspective.

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Article Synopsis
  • The study investigates the risk factors for oropharyngeal gonorrhea specifically among female and gender-diverse sex workers, addressing the lack of research in this area despite rising infection rates.
  • Conducted as a mixed methods case-control study in Australia from 2018 to 2020, it involved 83 sex workers with oropharyngeal gonorrhea and 581 without, along with interviews from 19 participants in Melbourne.
  • Key findings reveal that performing condomless fellatio is significantly linked to oropharyngeal gonorrhea, while most sex workers commonly use mouthwash and are cautious about condom use, highlighting the need for targeted prevention strategies.
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  • The study aimed to investigate changes in syphilis positivity rates among women and heterosexual men in major Australian cities from 2011 to 2019, focusing on various health determinants.
  • A total of 88,562 first tests were analyzed, revealing that the syphilis positivity rate increased for both groups over the years, with 0.34% of women and 0.66% of men testing positive.
  • Socio-economic disadvantage, Indigenous status, and recent injection drug use significantly contributed to higher positivity rates, while bisexual women and those engaged in recent sex work showed lower rates compared to heterosexual women.
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Objectives: To compare the usability and acceptability of oral fluid- and blood-based HIV self-test kits among men who have sex with men in Australia.

Design: Randomised crossover trial.

Setting, Participants: Gay, bisexual, and other men aged 18 years or older who have sex with men, who attended two metropolitan sexual health clinics in Sydney and Melbourne, 7 January - 10 December 2019.

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Background: Men who have sex with men are a risk group for anal human papillomavirus (HPV) and anal cancer. Australia introduced a universal school-based HPV vaccination program in 2013. Self-reported HPV vaccination status has been widely used in clinical and research settings, but its accuracy is understudied.

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Article Synopsis
  • The study investigates the prevalence of anal HPV and high-grade squamous intraepithelial lesions (HSIL) in men, focusing on factors like HIV status and sexual orientation.
  • Researchers conducted a systematic review and pooled individual data from 64 studies involving nearly 29,900 men to analyze type-specific HPV infection and HSIL occurrences.
  • Findings showed varying HPV prevalence rates: among HIV-negative MSW, HPV16 was at 1.8%, while HIV-positive MSM had rates as high as 28.5% for HPV16 and 74.3% for high-risk types, suggesting a significant impact of HIV on HPV infection rates.
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Objective: Chlamydia and gonorrhoea are common sexually transmitted infections that infect the oropharynx, anorectum and urethra in men who have sex with men (MSM). This study aimed to examine the pattern of infection at more than one site (multisite) for chlamydia and gonorrhoea among MSM.

Methods: This was a retrospective study of MSM attending the Melbourne Sexual Health Centre for the first time between 2018 and 2019.

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Objective: This study aimed to determine the frequency of mouthwash use and its association to oral sex practice in heterosexuals.

Design: A cross-sectional study.

Setting: Data obtained from a sexual health clinic in Victoria, Australia, between March 2019 and April 2019.

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BackgroundInternational travel is considered a risk factor for acquiring ; however, there are little empirical data to support this.AimTo examine the prevalence and risk factors for infections among heterosexual international travellers (n = 28,786) attending the Melbourne Sexual Health Centre (MSHC), Australia, compared to Australian residents (n = 20,614).MethodsWe conducted a repeated cross-sectional study and analysed sexual behaviours and chlamydia positivity among heterosexual males and females aged ≤ 30 attending MSHC for the first time between January 2007 and February 2017.

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Introduction: Gonorrhoea and chlamydia cases have been rising among gay, bisexual and other men who have sex with men (MSM) over the last decade. The majority of cases are extragenital and occur at the oropharynx and anorectum. The aim of this narrative review was to review the risk factors and mode of transmission for gonorrhoea and chlamydia at the oropharynx and anorectum among MSM.

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Objectives: There are limited data on the prevalence of (Mgen) coinfection with rectal chlamydia ( (CT)) and rectal gonorrhoea ( (NG)) infections and few studies examining the prevalence of pharyngeal Mgen in men who have sex with men (MSM). Using transcription-mediated amplification assay, this study aimed to determine the proportion of rectal CT and rectal NG infections in MSM who are coinfected with rectal Mgen, and the proportion of MSM with Mgen detected in the pharynx in order to inform clinical practice.

Methods: This was a cross-sectional study conducted at Melbourne Sexual Health Centre in Australia.

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Objective: The Victorian legislation requires sex workers to have quarterly screening for genital chlamydia and gonorrhoea, but screening for oropharyngeal infection is not mandatory in Victoria, Australia. In 2017, oropharyngeal screening for gonorrhoea and chlamydia was added as part of the routine quarterly screening for sex workers attending the Melbourne Sexual Health Centre (MSHC). The aim of this study was to examine the prevalence of oropharyngeal gonorrhoea and chlamydia among female sex workers (FSW).

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Introduction: Our aim was to describe trends in the number of bacterial sexually transmitted infections (STIs) diagnosed at Melbourne's sexual health clinic over a century.

Methods: A retrospective analysis of STI diagnoses (gonorrhoea, infectious syphilis and chancroid) among individuals attending Melbourne's sexual health service over 99 years between 1918 and 2016.

Results: Substantial increases in STI rates coincided with World War II, the 'Sexual Revolution of the 1960s and 1970s', and the last 10 years.

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Previous studies have shown that men who have sex with men (MSM) who use smartphone dating applications (apps) are at higher risk of gonorrhoea, but not HIV. We have hypothesised that kissing may be a risk factor for oropharyngeal gonorrhoea. We measured differences in kissing practices among MSM who use different methods to find male casual sexual partners (CSPs).

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Article Synopsis
  • The study aimed to identify how common Fanconi Syndrome (FS) is in patients taking tenofovir disoproxil fumarate (TDF) and what factors may contribute to its development.
  • A total of 1,442 patients were analyzed, and 13 cases of FS were found, with a higher incidence in those also taking ritonavir compared to those not taking it.
  • The findings suggest that co-administering ritonavir significantly increases the risk of developing FS, while traditional chronic kidney disease risk factors did not predict the syndrome's occurrence in TDF-treated patients.
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'Fuckbuddies' are a type of regular sexual partner with whom men have ongoing sexual contact, generally in the absence of romantic attachment. We surveyed 989 men who have sex with men (MSM) at the Melbourne Sexual Health Centre, Australia, with the aim of determining the frequency of 'fuckbuddy' partnerships among sexual health clinic attendees and assessing their sexual risk. The majority (60%) of 1139 regular partnerships were described as 'fuckbuddies'.

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Objectives: The aim of this study was to examine the willingness of men who have sex with men (MSM) to change their behaviours to potentially reduce the risk of pharyngeal gonorrhoea transmission and acquisition.

Methods: A cross-sectional questionnaire-based study was conducted among MSM attending the Melbourne Sexual Health Centre, Australia, between March and September 2015. Participants were asked how likely they would change their behaviours to reduce the risk of pharyngeal gonorrhoea.

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