Publications by authors named "Eric Obeng"
Purpose: To evaluate the short-term effect of intravitreal bevacizumab (avastin) injection on visual outcomes of patients with diabetic macular oedema.
Methods: A retrospective cross-sectional study was conducted to evaluate 39 eyes of thirty-nine patients (mean age ± SD: 61.4 ± 15.
As the world's population is increasing exponentially, human diets have changed to less healthy foods resulting in detrimental health complications. Increasing vegetable intake by both rural and urban dwellers can help address this issue. However, these communities often face the challenge of limited vegetable supply and accessibility.
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- Glioblastoma is the most aggressive brain tumor in adults, and phospholipase C β1 (PLCβ1) has been identified as a significant gene in the molecular classification of high-grade gliomas.
- The study shows that PLCβ1 levels are lower in glioblastoma samples compared to healthy controls, and its reduced expression is linked to more aggressive tumor behavior.
- Silencing PLCβ1 in brain cells leads to increased cell migration, invasion, and proliferation, suggesting PLCβ1 plays a role in maintaining a less aggressive tumor phenotype.
Phosphoinositides (PIs) are phosphorylated derivatives of phosphatidylinositol. They act as signaling molecules linked to essential cellular mechanisms in eukaryotic cells, such as cytoskeleton organization, mitosis, polarity, migration or invasion. PIs are phosphorylated and dephosphorylated by a large number of PI kinases and PI phosphatases acting at the 5-, 4- and 3- position of the inositol ring.
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