Lyme disease (LD) is the most common tick-borne illness across the United States, caused by the bacterium and transmitted to humans by the bite of infected ticks. Jamestown Canyon Virus (JCV) is an emerging mosquito-borne pathogen found mostly in the upper Midwest and Northeastern United States. Co-infection between these two pathogens has not been previously reported since it would require the host to be bitten by the two infected vectors at the same time.
View Article and Find Full Text PDFBACKGROUND Powassan virus (POWV) is an emerging tick-borne flavivirus transmitted to humans by ticks. While infection is asymptomatic in some people, others develop life-threatening encephalitis with high mortality rates. Co-infection between POWV and Borrelia burgdorferi is rare despite the fact that both pathogens can be transmitted through the same tick vector, Ixodes scapularis.
View Article and Find Full Text PDFLiver abscess associated with suppurative portal vein thrombosis (pylephlebitis) secondary to has been rarely reported. It is considered to be an abdominal variant of Lemierre's syndrome associated with significant morbidity and mortality. We report a case of 69-year-old man who developed liver abscess and pylephlebitis due to with an unclear source of infection.
View Article and Find Full Text PDFTo review the anatomic basis of prostate boundary selection on T2-weighted magnetic resonance imaging (MRI). To introduce an alternative 3D ellipsoid measuring technique that maximizes precision, report the intra- and inter-observer reliability, and to advocate it's use for research involving multiple observers. We demonstrate prostate boundary anatomy using gross pathology and MRI examples.
View Article and Find Full Text PDFPurpose: To evaluate MR imaging parameters including quantitative multiphasic post-contrast enhancement with subtraction and qualitative diffusion weighted imaging (DWI) in differentiating benign versus malignant portal venous thrombosis (PVT) in patients with hepatocellular carcinoma (HCC).
Method: Radiology reports over a 6-year period ending February 2016 were searched for key words indicating presence of both HCC and PVT on abdominal MRI. 39 patients were identified with PVT characterized as benign or malignant based on pathologic data or serial imaging growth criteria.
Purpose: To validate the application of a magnetic resonance imaging (MRI)-based lobar classification of benign prostatic hyperplasia (BPH) for use in research and clinical management.
Methods: Two radiologists with 5 and 11 years post-fellowship experience were trained in the lobar classification of BPH using an internally developed atlas of prostate anatomy with example MRI images edited by a third senior radiologist designated as the "administrator" of the study. A study population of 140 patients referred to a tertiary academic medical center with known or suspected prostate cancer was selected by the administrator to test the interrater reliability (IRR; precision) of the classification as well as accuracy of the two readers compared to the administrator as the "gold" standard.
BACKGROUND Babesiosis is an emerging, tick-borne zoonosis caused by intraerythrocytic protozoa of the genus Babesia. Babesia microti is the main pathogen causing human disease and is endemic in the northeastern and upper midwestern parts of the USA. Severity of infection ranges from mild, self-limited, febrile viral-like illness accompanied by nonspecific symptoms to life-threatening infection complicated by severe hemolytic anemia, disseminated intravascular coagulation (DIC), acute respiratory distress syndrome (ARDS), and renal or/and hepatic failure.
View Article and Find Full Text PDFA 47-year-old female presented to clinic with a 5-year history of a left buttock mass. The patient's hemoglobin was low (9.7 g/dL); laboratory analysis was otherwise unremarkable.
View Article and Find Full Text PDFHepatocellular carcinoma (HCC) is the 6th most common cancer worldwide. Imaging plays a critical role in HCC screening and diagnosis. Initial screening of patients at risk for HCC is performed with ultrasound.
View Article and Find Full Text PDFLipiduria, also known as lipuria, refers to the presence of lipids within the urine. When lipids are present in macroscopic quantities, lipiduria can be visualized as a fat-fluid level on computed tomography imaging. Although the general differential diagnosis of lipiduria is broad, reported etiologies of lipiduria diagnosed by computed tomography have primarily included chyluria, urine-induced lipolysis, and trauma.
View Article and Find Full Text PDFObjectives: To assess the feasibility of low-dose time-resolved imaging of contrast kinetics (TRICKS) magnetic resonance (MR) angiography of the pedal vasculature at 3.0 Tesla (T) using a head coil.
Materials And Methods: Eleven healthy volunteers were imaged using TRICKS MR angiography at 3.
Objective: Although there is a well-recognized association between thymic hyperplasia and benign thyroid disorders, the prevalence of thymic hyperplasia in patients with malignant thyroid diseases has not been previously reported. We performed this study to determine the prevalence and morphologic features of thymic hyperplasia on CT scans of thyroid cancer patients.
Conclusions: Thymic hyperplasia is commonly observed on CT scans of thyroid cancer patients and almost always demonstrates a characteristic pyramidal configuration.
Objective: The mechanism by which nonarteritic anterior ischemic optic neuropathy (NAION) causes an infarct in the optic nerve is controversial. We studied the three-dimensional anatomic configuration of a NAION infarct to better elucidate its pathophysiology.
Design: Case report with clinicopathologic correlation.