Regional trends in colorectal cancer mortality in people aged 45-84 years in the US, 1999-2022.

Background: Colorectal cancer (CRC) screening via colonoscopy is now advised for most adults beginning at age 45 years, an update from the earlier recommendation of age 50 years. With the increase in CRC screening rates, it is crucial to examine how mortality rates have changed over time. The aim of this study is to identify trends and regional differences in CRC mortality over the last two decades, specifically in individuals within the CRC recommended screening age group.

Description of the NASA GEOS Composition Forecast Modeling System GEOS-CF v1.0.

The Goddard Earth Observing System composition forecast (GEOS-CF) system is a high-resolution (0.25°) global constituent prediction system from NASA's Global Modeling and Assimilation Office (GMAO). GEOS-CF offers a new tool for atmospheric chemistry research, with the goal to supplement NASA's broad range of space-based and in-situ observations.

Evidence-based medicine curricula and barriers for physicians in training: a scoping review.

Objectives: To describe the published literature on EBM curricula for physicians in training and barriers during curriculum implementation.

Methods: We performed a systematic search and review of the medical literature on PubMed, Embase, ERIC, Scopus and Web of Science from the earliest available date until September 4, 2019.

Results: We screened 9,042 references and included 29 full-text studies and 14 meeting abstracts.

Remission of a Perimyocardial Melanoma Metastasis With Pembrolizumab Treatment.

Malignant melanoma demonstrates the highest rate of cardiac metastases. The incidence of melanoma is rising. The prognosis of people with advanced melanoma is generally poor.

Chemical Mechanisms and Their Applications in the Goddard Earth Observing System (GEOS) Earth System Model.

NASA's Goddard Earth Observing System (GEOS) Earth System Model (ESM) is a modular, general circulation model (GCM), and data assimilation system (DAS) that is used to simulate and study the coupled dynamics, physics, chemistry, and biology of our planet. GEOS is developed by the Global Modeling and Assimilation Office (GMAO) at NASA Goddard Space Flight Center. It generates near-real-time analyzed data products, reanalyses, and weather and seasonal forecasts to support research targeted to understanding interactions among Earth System processes.

Frequency and Impact of Summertime Stratospheric Intrusions over Maryland during DISCOVER-AQ (2011): New Evidence from NASA's GEOS-5 Simulations.

Aircraft observations and ozonesonde profiles collected on July 14 and 27, 2011, during the Maryland month-long DISCOVER-AQ campaign, indicate the presence of stratospheric air just above the planetary boundary layer (PBL). This raises the question of whether summer stratospheric intrusions (SIs) elevate surface ozone levels and to what degree they influence background ozone levels and contribute to ozone production. We used idealized stratospheric air tracers, along with observations, to determine the frequency and extent of SIs in Maryland during July 2011.

Palliative care consultations in hospitalized stroke patients.

Objective: To determine the pattern and characteristics of palliative care (PC) consultations in patients with stroke and compare them with the characteristics of nonstroke consultations.

Methods: The palliative care program at Strong Memorial Hospital (SMH) was established in October 2001. SMH is a 765-bed academic medical center with approximately 38,000 discharges.

Ambulatory blood pressure monitoring after 1 year on valsartan or amlodipine-based treatment: a VALUE substudy.

Objective: The ambulatory blood pressure (ABP) monitoring substudy of the Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial was carried out in a subset of patients from USA, Italy and Denmark. ABP was measured after 1 year in the trial, with the aim of evaluating comparability of ABP levels on valsartan (VAL) and amlodipine (AML)-based regimens.

Methods: ABP was measured every 20 min during a 25-h period after morning administration of medicine; 659 patients were available for intention-to-treat analysis.

A dynamical calibration of the mass-luminosity relation at very low stellar masses and young ages.

Mass is the most fundamental parameter of a star, yet it is also one of the most difficult to measure directly. In general, astronomers estimate stellar masses by determining the luminosity and using the 'mass-luminosity' relationship, but this relationship has never been accurately calibrated for young, low-mass stars and brown dwarfs. Masses for these low-mass objects are therefore constrained only by theoretical models.

Host Suitability of Rapeseed for Heterodera schachtii.

Because rapeseed, especially canola, has the potential to be grown in rotation with sugarbeet in the north-central region of the United States, this study was initiated to assess its susceptibility to infection by Heterodera schachtii and to develop a screening method for Brassica germplasm. Existing methodology was adapted for growing Brassica juncea, B. napus, B.

Are seedlings from small seeds always inferior to seedlings from large seeds? Effects of seed biomass on seedling growth in Pastinaca sativa L.

Previous field studies of recruitment in Pastinaca sativa L. indicate that more seedlings from small seeds than from large seeds survive short-term droughts. To explore this phenomenon, the effects of variation in seed biomass in Pastinaca sativa on embryo size and seedling characteristics 10, 20, 30 and 40 days after emergence were investigated.