Preferences for herpes zoster vaccination among adults aged 50 years and older in the United States: results from a discrete choice experiment.

Background: Most adults, and disproportionately fewer African-Americans, have not received herpes zoster (HZ) vaccination despite current recommendations. This study (GSK study identifiers: 208677/HO-17-18066) assessed HZ vaccination preferences among adults aged ≥ 50 years.

Research Design And Methods: In this discrete choice experiment, respondents chose among a 'no vaccine' option and two HZ vaccine profiles, characterized by seven attributes, in a series of choice questions.

Validation of a quality-of-life instrument for laryngopharyngeal reflux.

Objectives: To establish the reliability, validity, and responsiveness of a new, disease-specific assessment tool, the LPR-HRQL, which assesses patient-reported outcomes (PRO) with regard to health-related quality of life (HRQL) of patients with laryngopharyngeal reflux (LPR).

Design: A prospective, open-label, repeated-measures study.

Setting: Six centers in 4 states in the eastern United States.

The impact of laryngopharyngeal reflux on patient-reported quality of life.

Objectives/hypothesis: The objectives were to assess patient-reported outcomes, specifically, the health-related quality of life of patients with laryngopharyngeal reflux, and to compare those reported levels with the health-related quality of life of patients with gastroesophageal reflux disease and a general population.

Study Design: Prospective study.

Methods: As part of a prospective study to validate a health-related quality of life instrument for laryngopharyngeal reflux, patient-reported data were collected before the initiation of therapy.