Publications by authors named "Eric Ley"

Background: Vascular surgery board eligibility may be secured through 5+0 integrated programs (IV) as well as 5+2 general surgery/vascular fellowship pathway (VF). We hypothesized that IV graduates accrue less experience relevant to vascular trauma than VF graduates. We assessed the first decade of IV graduate experience and compared it to contemporaneous VF graduates.

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Introduction: Hepatic angioembolization is highly effective for hemorrhage control in hemodynamically stable patients with traumatic liver injuries and contrast extravasation. However, there is a paucity of data regarding the specific location of angioembolization within the hepatic arterial vasculature and its implications on patient outcomes.

Methods: A post-hoc analysis of a multicenter prospective observational study across 23 centers was performed.

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Background: Prior studies evaluating observation versus angioembolization (AE) for blunt liver injuries (BLT) with contrast extravasation (CE) on computed tomography imaging have yielded inconsistent conclusions, primarily due to limitations in single-center and/or retrospective study design. Therefore, this multicenter study aims to compare an observation versus AE-first approach for BLT, hypothesizing decreased liver-related complications (LRCs) with observation.

Methods: We conducted a post hoc analysis of a multicenter, prospective observational study (2019-2021) across 23 centers.

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Article Synopsis
  • The study examines the impact of illicit substance use during pregnancy, noting a 4-fold increase over two decades and its negative effects on mothers and fetuses.
  • A multicenter retrospective analysis from 2016 to 2021 included 852 pregnant trauma patients (PTPs), with 9.8% testing positive for substances, primarily THC and methamphetamine.
  • Findings showed that PTPs with positive urine toxicology had higher rates of blunt head injuries, extremity injuries, domestic violence incidents, and uterine contractions, but similar maternal complication rates compared to those who tested negative.
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  • Current guidelines suggest that patients with isolated sternal fractures (ISFs) and minor heart-related issues should undergo 24-hour telemetry monitoring, despite a single study indicating they might not need it.
  • A study conducted across 8 trauma centers reviewed ISF patients with minor ECG changes or troponin elevation and found that very few (1.6%) experienced significant blunt cardiac injury (BCI), and none had BCI diagnosed via echocardiogram.
  • The results imply that routine monitoring and echocardiography may not be necessary for ISF patients displaying minor ECG abnormalities and challenge existing medical protocols.
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Background: Venous thromboembolism (VTE) in critically ill patients has been well-studied in Western countries. Many studies have developed risk assessments and established pharmacological protocols to prevent deep venous thrombosis (DVT). However, the DVT rate and need for pharmacologic VTE prophylaxis in critically ill Taiwanese patients are limited.

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  • Almost 10% of pregnant women experience serious injuries, but how serious injuries affect them and their babies isn’t well understood.
  • A study looked at 950 pregnant women with injuries and found that about 3.4% had severe injuries, which led to more complications and higher risks for both the mother and baby.
  • Severely injured women had more surgeries and a higher chance of losing their baby, so doctors need to be very careful when taking care of them.
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  • High-grade liver injuries with extravasation (HGLI + Extrav) carry significant risks, and the study evaluated whether an observation-first strategy (OBS) is safe compared to initial angiography (IR).
  • Of 59 patients, 39% were treated with OBS and 61% with IR, with patients initially managed by IR experiencing a higher rate of surgery (13.9% vs. 0%).
  • Despite the increased rate of operations for IR patients, there were no significant differences in liver-related complications or mortality, indicating that OBS may be a suitable approach for selectively managing HGLI + Extrav patients.
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Trauma patients are at an elevated risk for developing venous thromboembolism (VTE), which includes pulmonary embolism and deep vein thrombosis. In the inpatient setting, prompt pharmacologic prophylaxis is utilized to prevent VTE. For patients with lower extremity fractures or limited mobility, VTE risk does not return to baseline levels postdischarge.

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  • Doctors often use CT scans to check for injuries after car accidents, but for pregnant women, these scans can be risky for the baby.
  • A study looked at how often pregnant women involved in car crashes got CT scans at 12 different hospitals from 2016 to 2021.
  • The results showed a big difference in the number of scans given at each hospital, suggesting there should be clearer rules to keep both moms and babies safe while still finding any injuries.
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Background: Pregnant trauma patients (PTPs) undergo observation and fetal monitoring following trauma due to possible fetal delivery (FD) or adverse outcome. There is a paucity of data on PTP outcomes, especially related to risk factors for FD. We aimed to identify predictors of posttraumatic FD in potentially viable pregnancies.

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  • The study looked at the effects of pregnancy in older moms (35 years and older) who had trauma and compared them to younger pregnant moms.
  • It found that older moms had more injuries to certain organs like the pancreas and stomach, but there was no difference in the chance of delivering the baby after trauma.
  • Because of this, they decided that older moms don’t need extra monitoring compared to younger moms after a trauma.
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Objective: Antithrombin III (ATIII) deficiency may result from hereditary or acquired reduction in ATIII levels and is associated with an increase in venous thromboembolism (VTE) in the general population. VTE is a potentially preventable complication in the critically ill surgical patients. The objective of this study was to evaluate the relation between ATIII levels and VTE in surgical intensive care unit (SICU) patients.

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Background: Patients with traumatic brain injury (TBI) are at high risk of venous thromboembolism (VTE). Recent guidelines recommend starting TBI patients on enoxaparin 30 mg twice daily and then considering weight-based dosing. Creatinine clearance may be better than weight for patients when considering high and low enoxaparin dose requirements.

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Introduction: Guidelines encourage higher doses of low molecular weight heparin (LMWH) for prophylaxis in trauma patients. The risks of LMWH must be considered for patients who require an epidural catheter. We compared adequate and inadequate prophylaxis to determine if venous thromboembolism (VTE) and complication rates differed among patients with epidural catheters.

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  • The study investigates survival rates of trauma patients who received closed chest compressions, focusing on different age groups from 2015 to 2020 across four trauma centers.
  • Among the 247 patients analyzed, the overall mortality rate was 92%, with patients aged 70 and older showing 100% mortality and no survivors to hospital discharge.
  • Findings suggest that closed chest compressions may have limited effectiveness in older adults, potentially guiding decisions on whether to proceed with such interventions in this population.
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Background: Guidelines for enoxaparin dosing after trauma recommend an initial dose of 40 mg twice daily for most patients and then adjusting by anti-Xa levels. Previous studies indicated higher enoxaparin doses are necessary with higher levels of creatinine clearance (CrCl). We sought to determine if the goal enoxaparin dose correlates with the admission CrCl to reduce the reliance on measuring anti-Xa levels.

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Venous thromboembolism (VTE) is a major issue in trauma patients. Without prophylaxis, the rate of deep venous thrombosis approaches 60% and even with chemoprophylaxis may be nearly 30%. Advances in VTE reduction are imperative to reduce the burden of this issue in the trauma population.

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Trauma patients are at high risk for venous thromboembolism (VTE). Despite evidence-based guidelines and concerted efforts in trauma centers to implement optimal chemoprophylaxis strategies, VTE remains a frequent diagnosis in trauma patients. Current chemoprophylaxis strategies largely focus on the subcutaneous injection of low-molecular-weight heparin, which is administered twice daily.

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Background: The Western Trauma Association (WTA) has undertaken publication of best practice clinical practice guidelines on multiple trauma topics. These guidelines are based on scientific evidence, case reports, and best practices per expert opinion. Some of the topics covered by this consensus group do not have the ability to have randomized controlled studies completed because of complexity, ethical issues, financial considerations, or scarcity of experience and cases.

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