Publications by authors named "Eric Le Balc'h"
Background: There are no studies on incidental anal F-fluorodeoxyglucose (FDG) uptake.
Aim: To assess the rate and aetiologies of incidental anal FDG uptake and to evaluate the correlation between FDG positron-emission tomography/computed tomography (PET/CT) parameters and the diagnosis of an anorectal disease.
Methods: The data from patients with incidental anal FDG uptake were retrospectively analysed.
Background & Aims: Infliximab increases the risk of infection in patients with inflammatory bowel diseases (IBD), but there is controversy over the relationship between drug concentration and infections. We aimed to assess factors associated with infection in infliximab-treated patients, including pharmacokinetic features.
Methods: We collected data from 209 patients with IBD (102 men; mean age, 39 y; 159 with Crohn's disease; 54 received combination therapy) who received an infliximab maintenance regimen from November 2016 through April 2017 in France.
Article Synopsis
- The study investigates the presence of N-acyl homoserine lactones (AHLs), key bacterial communication molecules, in fecal samples from healthy individuals and patients with inflammatory bowel disease (IBD).
- Using techniques like mass spectrometry and sequencing, researchers identified 14 AHLs, highlighting 3-oxo-C12:2, which was found less frequently in IBD patients and linked to healthier gut microbiota.
- The prominent AHL, 3-oxo-C12:2, exhibited anti-inflammatory effects on gut cells, suggesting its potential role in protecting gut health amid IBD.
All tumors have in common to reactivate a telomere maintenance mechanism to allow for unlimited proliferation. On the other hand, genetic instability found in some tumors can result from the loss of telomeres. Here, we measured telomere length in colorectal cancers (CRCs) using TRF (Telomere Restriction Fragment) analysis.
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