Publications by authors named "Eric Koza"
The strength of a systematic review hinges in large part on the quality of evidence it appraises. Observational studies, including cohort studies and case series, are positioned lower on the hierarchy of evidence, with cohort studies typically higher than case series. The often subtle differences between these study designs may lead to misclassification and can impact the strength of recommendations derived from such data.
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- The FDA regulates medical devices to make sure they are safe and work well before they can be sold.
- A survey was done to understand how the FDA's Medical Devices Advisory Committee makes decisions and what could be improved.
- Out of 92 panel members, most were men and white, and many thought the information from the FDA was fair and that important trials were often designed well.
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- A study was conducted to analyze how often dermatologic surgeons face challenges in identifying the locations of skin cancer tumors before surgery.
- Out of over 17,000 cases, only 0.60% involved uncertain sites, with these cases more common in older, male patients who had biopsies done over a month prior.
- Surgeons commonly used various methods to confirm tumor locations, achieving success in identifying 82% of these uncertain sites, while some surgeries were delayed, especially for non-facial tumors.
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- Acne scarring, resulting from inflammation common in many individuals, negatively affects self-esteem and social acceptance, prompting a search for effective treatments.
- A study evaluated the effectiveness of multiple subcision treatments on rolling acne scars, enrolling five patients who received treatment on one side of their face while the other side served as a control.
- Results showed that the treated side had significantly greater improvements in scar appearance and patient satisfaction compared to the untreated side, indicating that subcision may effectively enhance the appearance of rolling acne scars.
Therapeutic options for acne scars include subcision and suction with microdermabrasion, but these treatment modalities have not been studied in conjunction. To compare effectiveness of subcision alone versus subcision with suction for the treatment of facial acne scars. Randomized, split-faced, evaluator-blinded control trial.
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- Inconsistent reporting of outcomes in rosacea clinical trials is hindering accurate data analysis and meta-analyses, highlighting the need for standardized outcome measures.
- A core outcome set (COS) was developed through systematic literature reviews and a Delphi process, involving feedback from physicians and patients to identify essential outcomes in rosacea trials.
- The final COS includes 8 key domains, such as skin symptoms and patient satisfaction, which aim to enhance the comparability and relevance of future rosacea research and interventions.
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- Surgical site infections (SSIs) are linked to higher health costs and complications, and a study analyzed 45,445 cases to identify contributing factors.
- Higher SSI rates were found in individuals who were obese, tobacco users, diabetic, had multiple comorbidities, or stayed longer in medium-to-large hospitals, whereas lower rates occurred in older adults, females, underweight patients, or those in smaller hospitals.
- Recognizing these risk factors can help surgeons better anticipate and manage potential complications related to SSIs.
Background: The history of intracranial hemorrhage (ICrH) is considered a contraindication for intravenous thrombolysis (IVT) among patients with acute ischemic stroke (AIS). Objective: This study aimed at comparing the safety of IVT among patients with and without a history of ICrH.
Methods: We performed a systematic review of the literature.
Importance: Transient ischemic attack (TIA) often indicates a high risk of subsequent cerebral ischemic events. Timely preventive measures improve the outcome.
Objective: To estimate and compare the risk of subsequent ischemic stroke among patients with TIA or minor ischemic stroke (mIS) by care setting.
Various studies on oral anticoagulants (OAC) use among atrial fibrillation (AF) patients have shown high rates of undertreatment and the presence of sex disparity. This study used the 'Geisinger Neuroscience Ischemic Stroke' (GNSIS) database to examine sex differences in OAC treatment among ischemic stroke patients with the pre-event diagnosis of AF in rural Pennsylvania between 2004 and 2019. We examined sex disparities in OAC undertreatment and associated risks based on age group and ischemic stroke year.
View Article and Find Full Text PDFSince the early days of the pandemic, there have been several reports of cerebrovascular complications during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Numerous studies proposed a role for SARS-CoV-2 in igniting stroke. In this review, we focused on the pathoetiology of stroke among the infected patients.
View Article and Find Full Text PDFBackground: SARS-CoV-2 infected patients are suggested to have a higher incidence of thrombotic events such as acute ischemic strokes (AIS). This study aimed at exploring vascular comorbidity patterns among SARS-CoV-2 infected patients with subsequent stroke. We also investigated whether the comorbidities and their frequencies under each subclass of TOAST criteria were similar to the AIS population studies prior to the pandemic.
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