Radiofrequency ablation of hepatocellular carcinoma guided by real-time physics-based ablation simulation: a prospective study.

Objectives: To assess the safety and efficacy of radiofrequency ablation (RFA) guidance software that incorporated patient-specific physics-based simulation of each ablation volume.

Materials And Methods: Patients referred for curative ablation of hepatocellular carcinoma (HCC) of 2-5 cm diameter were prospectively enrolled. RFA was performed under general anesthesia.

Cholecystokinin to Enhance the Safety of Ablation of Liver Tumors Adjacent to the Gallbladder.

This retrospective case review describes the potential for intravenous cholecystokinin (CCK) to improve the safety margin between the hepatic tumor and gallbladder (GB) for hepatic tumor ablation. Eight patients with primary hepatic neoplasms adjacent to the GB underwent CCK administration before ablation. GB volume and contact area measurements were performed before and after CCK administration to assess the degree of contraction.

Gunther Tulip Filter Strut Penetration: Benign Long-Term Follow-up.

Purpose: To describe the natural history of Gunther Tulip filter (GTF) strut penetration based on the computed tomography (CT)-documented distance penetrated over time and any clinical manifestations.

Materials And Methods: The records of 203 patients (mean age, 59.1 years; 59.

CT characterization of retractor related liver injuries after pancreaticoduodenectomy: Retrospective analysis of a single institution experience.

Purpose: Retractor related liver injuries (RRLI) are reported after upper gastrointestinal tract surgeries; most commonly laparoscopic cholecystectomy and gastric surgeries. The aim of this study was to characterize the incidence, identification, type, severity, clinical features and risk factors for RRLI after open and robotic pancreaticoduodenectomy.

Methods: A 6-year retrospective study of 230 patients was performed.

Validation of Software for Patient-Specific Real-Time Simulation of Hepatic Radiofrequency Ablation.

Rationale And Objectives: CT-guided radiofrequency ablation (RFA) is a potentially curative minimally invasive treatment for liver cancer. Local tumor recurrence limits the success of RFA for large or irregular tumors as it is difficult to visualize the tissue destroyed. This study was designed to validate a real-time software-simulated ablation volume for intraprocedural guidance.

Activation of stem cell up-regulation/mobilization: a cardiovascular risk in both mice and humans with implications for liver disease, psoriasis and SLE.

Experimentally induced injury triggers up-regulation and mobilization of stem cells in mice that causes accelerated atherosclerosis. mice have chronic activation of stem cell up-regulation/mobilization and accelerated atherosclerosis. In addition, the mice have elevation of serum cytokines G-CSF, IL-17 and IL-23, each necessary for stem cell mobilization.

Liver Abscesses: Factors That Influence Outcome of Percutaneous Drainage.

Objective: The purpose of this study was to identify the details of percutaneous catheter drainage (PCD) of pyogenic liver abscesses, the etiologic factors, and the management techniques that contribute to successful treatment.

Materials And Methods: The records of 75 consecutively registered patients who underwent PCD of 96 abscesses at a single institution between May 2009 and May 2014 were retrospectively reviewed. Thirty-nine patients (52%) were oncology patients, and 36 (48%) had recently undergone abdominal surgery.

Hypersplenism in liver disease and SLE revisited: current evidence supports an active rather than passive process.

Background: Active and passive theories have been advanced to explain splenomegaly and cytopenias in liver disease. Dameshek proposed active downregulation of hematopoiesis. Doan proposed passive trapping of blood components in a spleen enlarged by portal hypertension.

Transhepatic Embolization of Congenital Intrahepatic Portosystemic Venous Shunts with Associated Aneurysms.

Intrahepatic shunts between the portal and systemic venous systems with associated aneurysms are extremely rare. A middle aged woman presented with hepatic encephalopathy and was found to have two intrahepatic portosystemic venous shunts with associated aneurysms. Diagnosis was made by duplex ultrasound and was confirmed with contrast enhanced MRI.