Oxidative Stress and Cancer Risk in Schistosomiasis.

Schistosomiasis is considered one of the most devastating parasitic diseases globally, coming second only to malaria in terms of morbidity. The disease-causing parasite can inhabit the body for over a decade, leading to imbalances in the host's metabolic systems. The flukes and their eggs can illicit various immunological and metabolic complications resulting in the generation of reactive oxygen species (ROS).

Intestinal microbiome-rheumatoid arthritis crosstalk: The therapeutic role of probiotics.

Rheumatoid arthritis (RA) is a common systemic autoimmune disease with a global health importance. It is characterized by long-term complications, progressive disability and high mortality tied to increased social-economic pressures. RA has an inflammatory microenvironment as one of the major underlying factors together with other complex processes.

Leaf Extract Reverses Alloxan/Nicotinamide-Induced Diabetes Mellitus in Rats through Hormonal (Insulin, GLP-1, and Glucagon) and Enzymatic (-Amylase/-Glucosidase) Modulation.

Background: is used in folk medicine across Afro-Asian regions of the world. Earlier, glucose lowering and pancreato-protective effects of leaf extract (APLE) was confirmed experimentally in STZ/nicotinamide-induced diabetic rats; however, the underlying mechanism of antidiabetic effect and pancreato-protection remained unknown.

Objective: This study elucidated antidiabetic mechanisms and pancreato-protective effects of APLE in diabetic rats.

Seed Extract Attenuates the Ethanol-Induced Gastric Ulcer in Rats via the Inhibition of TNF- and INF- Levels and Modulation in the Expression of Ki67 Protein.

has been used to treat an upset stomach in African traditional medicine, but its efficacy and safety have not been scientifically studied. The present research is aimed at assessing the antiulcer property of the seed extract of the plant to validate its traditional claim. Rats were pretreated with three doses of aqueous extract of .

Infection, Virulence Genes' Distribution and Accompanying Clinical Outcomes: The West Africa Situation.

Data on () infection and virulence factors in countries across West Africa are scattered. This systematic review seeks to present an update on the status of infection focusing on prevalence rate, distribution of virulent genes, and their link to clinical outcomes across countries in the western part of Africa. This information is expected to broaden the knowledge base of clinicians and researchers regarding infection and associated virulence factors in West African countries.

Anti-inflammatory, anti-nociceptive and antipyretic activity of young and old leaves of Vernonia amygdalina.

Background: Both young and old leaves of Vernonia amygdalina (VA) are traditionally used to treat inflammation, pain and fever. However, the efficacy of young and old leaves for treating these ailments have not been compared till date.

Aim: To ascertain the effect of young and old leaves of VA in managing inflammation, pain and fever.

Corrigendum to "Antidiabetic Effect of Young and Old Ethanolic Leaf Extracts of : A Comparative Study".

[This corrects the article DOI: 10.1155/2016/8252741.].

Antidiabetic Effect of Young and Old Ethanolic Leaf Extracts of Vernonia amygdalina: A Comparative Study.

The young leaves of Vernonia amygdalina are often utilized as vegetable and for medicinal purpose compared to the old leaves. This study was designed to evaluate and compare the antidiabetic effects between ethanolic leaf extracts of old and young V. amygdalina on streptozotocin (STZ) induced diabetic rat for four weeks.