Publications by authors named "Eric Gundersen"
Bioorg Med Chem Lett
April 2005
Article Synopsis
- Alzheimer's disease (AD) is linked to the buildup of beta amyloid (Abeta) in the brain, contributing to its debilitating effects.
- Targeting gamma-secretase, an enzyme that produces Abeta, could be a potential treatment strategy for AD.
- The text outlines a series of gamma-secretase inhibitors developed from a specific scaffold found through a ROCS search in a corporate database.
