Publications by authors named "Eric Ginoux"
Background: The female reproductive tract (FRT) mucosa is the first line of defense against sexually transmitted infection (STI). FRT environmental factors, including immune-cell composition and the vaginal microbiota, interact with each other to modulate susceptibility to STIs. Moreover, the menstrual cycle induces important modifications within the FRT mucosa.
View Article and Find Full Text PDFEffective treatments against Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) are urgently needed. Monoclonal antibodies have shown promising results in patients. Here, we evaluate the in vivo prophylactic and therapeutic effect of COVA1-18, a neutralizing antibody highly potent against the B.
View Article and Find Full Text PDFThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is continuing to disrupt personal lives, global healthcare systems, and economies. Hence, there is an urgent need for a vaccine that prevents viral infection, transmission, and disease. Here, we present a two-component protein-based nanoparticle vaccine that displays multiple copies of the SARS-CoV-2 spike protein.
View Article and Find Full Text PDFArticle Synopsis
- Human cytomegalovirus (HCMV) infections in pregnant women can cause serious health issues for newborns due to congenital transmission.
- Recent advancements show that there are billions of DNA fragments in the bloodstream that can be analyzed for non-invasive prenatal testing (NIPT).
- The study found a way to identify HCMV DNA in NIPT data and created a statistical model to measure viral load, aiming to enhance the accuracy of NIPT for detecting HCMV during pregnancy.