Efficient RNA structure comparison algorithms.

Recently proposed relative addressing-based ([Formula: see text]) RNA secondary structure representation has important features by which an RNA structure database can be stored into a suffix array. A fast substructure search algorithm has been proposed based on binary search on this suffix array. Using this substructure search algorithm, we present a fast algorithm that finds the largest common substructure of given multiple RNA structures in [Formula: see text] format.

Acute orbital edema causing reversible blindness after the administration of intravenous contrast agent in a patient with thyroid eye disease.

A 55-year-old white woman with severe thyroid eye disease developed marked orbital edema following the administration of intravenous contrast media with complete loss of vision over a 10-minute period while in the radiology waiting room. She was immediately treated with intravenous methylprednisolone with recovery of precontrast visual acuity and resolution of orbital edema. She underwent orbital decompression 2 weeks later and is currently doing well.