[Development of a myasthenia crisis during interferon treatment for chronic C hepatitis].

If myasthenia gravis is not a usual complication of interferon therapy, several cases have been described with the use of theses molecules in the treatment of hepatitis C, cancer or multiple sclerosis. We report a new case of serious myasthenia gravis during interferon alpha and ribavirin therapy for hepatitis C.

[Macrophage activation syndrome after treatment with infliximab for fistulated Crohn's disease].

Introduction: Macrophage activation syndrome has never been reported as an adverse effect of infliximab.

Case: Treatment with infliximab was prescribed for a 37-year-old man with fistulated Crohn's disease unresponsive to azathioprine. Three months after the last injection, he developed macrophagic activation syndrome, with febrile pancytopenia, hyperferritinemia, hypertriglyceridemia and an activated cephalin time twice the control level.