Background: Selective inversion recovery quantitative magnetization transfer (SIR-qMT)-derived macromolecular to free water pool size ratio (PSR) and diffusion tensor imaging (DTI)-derived radial diffusivity (RD) are potential metrics for assessing myelin integrity in multiple sclerosis (MS). However, establishing their accuracy in identifying tissue injury is essential for clinical translation.
Purpose: To compare the accuracy and Cohen's effect size (ES) of PSR and RD in detecting and quantifying tissue injury in early MS.
The article examines several stochastic layers of epistemic reasoning at work in econometrics and in the current economic methods: (1) the argumentative level; (2) the reasoning based on the analogy with gambling; (3) the models based on analytical calculation of probabilities, where the phenomenon is held centered, its uncertainty being controlled by white noise as to its fluctuation; (4) the axiomatic calculus. Entanglement of these strata is observed. The article calls for reflexion on the topic.
View Article and Find Full Text PDFTwo brain regions with established roles in reading are the posterior middle temporal gyrus and the posterior fusiform gyrus (FG). Lesion studies have also suggested that the region located between them, the posterior inferior temporal gyrus (pITG), plays a central role in word recognition. However, these lesion results could reflect disconnection effects since neuroimaging studies have not reported consistent lexicality effects in pITG.
View Article and Find Full Text PDFOver the last two decades, history and social sciences have experienced a kind of merging, and a vast number of specialized domains have emerged. Yet the durkheimian register of "general sociology" seems somehow neglected. Firstly, this article analyzes the reasons for this neglect, and secondly, it indicates how, through a long-term reflexivity, one can formulate a new agenda for general sociology.
View Article and Find Full Text PDFOver the last two decades, history and social sciences have experienced a kind of merging, and a vast number of specialized domains have emerged. Yet the durkheim - ian register of "general sociology" seems somehow neglected. Firstly, this article analyzes the reasons for this neglect, and secondly, it indicates how, through a long-term reflexivity, one can formulate a new agenda for general sociology.
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