Design and mechanical evaluation of a novel fiber-reinforced scaffold for meniscus replacement.

A fiber-reinforced degradable scaffold for replacement of meniscal tissue was designed, fabricated, and mechanically evaluated. The hypotheses were that (1) the fiber network design would share a portion of compressive loads via the generation of circumferential tensile loads, and (2) the scaffold tensile properties would be similar to those of the meniscus. Two meniscus scaffold designs varying in fiber content (1000 or 500 fibers: MS1000, MS500) underwent cyclic compressive loading up to 100 and 250N, with resultant tensile loads measured at the anterior and posterior anchors.