Publications by authors named "Eri Takeshima"
Article Synopsis
- Bleeding from the gastrointestinal tract is a serious health issue that can lead to high rates of illness and death, particularly in everyday clinical scenarios.
- The gastrointestinal symptoms associated with Henoch-Schönlein purpura (HSP) are generally considered self-resolving, with little long-term impact on health.
- This report highlights a severe case of HSP in a male patient who experienced significant complications, including abdominal pain and gastrointestinal bleeding, despite treatment, underscoring the need for more research to improve HSP management in similar cases.
Do we have to perform a renal biopsy? Clinical dilemmas in a case with nephrotic syndrome.
Clin Med Insights Case Rep
August 2014
Renal biopsy is one of the pivotal diagnostic tools used in the field of nephrology. A morphological analysis of the kidney may also be of value for the overall management of patients with diabetic nephropathy. However, the indications for renal biopsy differ considerably among nephrologists, and no global consensus regarding performing this procedure among diabetic patients with various renal manifestations has yet been achieved.
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- A case study is presented of a patient with hepatitis B virus (HBV) who developed type II mixed cryoglobulinemia, leading to skin issues and kidney disease.
- The patient's skin symptoms improved alongside lower levels of cryoglobulin and HBV after treatment with oral entecavir and plasmapheresis.
- Ultimately, the patient needed prednisolone due to insufficient response from initial treatments, raising concerns about steroid use in similar cases complicated by HBV.
A 70-year-old man complained of muscle pain in his neck, shoulders and pelvic girdle. Proteinuria and hematuria subsequently developed. Blood analysis showed increased acute phase reactants.
View Article and Find Full Text PDFRapidly progressive glomerulonephritis (RPGN) is characterized by the rapid deterioration of the renal function associated with crescent formation on renal biopsies. This report describes a case of RPGN caused by anti-glomerular basement membrane (GBM) glomerulonephritis in an elderly man with severe thrombocytopenia and a platelet count of 1.4 × 10(4)/µL.
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- * Despite negative tests for HIV and hepatitis B and C, the patient's immune response was found to involve anti-PR3-ANCA antibodies and hypocomplementemia.
- * Treatment with rituximab improved her kidney function and nephrotic syndrome symptoms, but did not help with her periodic fever; genetic testing suggested a rare mutation linked to adult-onset hereditary periodic fever.
Article Synopsis
- Klotho is a protein linked to aging, and this study aimed to explore its levels in relation to kidney function in chronic kidney disease (CKD) patients.
- Researchers analyzed serum and urine samples from 131 CKD patients using a specific testing method, discovering a wide range in urinary Klotho excretion and serum levels.
- Findings showed that urinary Klotho levels (rather than serum levels) were significantly associated with kidney function, indicating that urinary Klotho may better reflect the number of functioning nephrons in CKD patients.
Article Synopsis
- Klotho is an anti-aging protein found in the kidneys and brain, and this study aimed to explore its connection to kidney function in patients undergoing chronic peritoneal dialysis (PD).
- Researchers measured soluble Klotho levels in serum, urine, and peritoneal dialysate from 36 PD patients, finding significant variability in urinary Klotho excretion that correlated with residual kidney function, while serum levels did not show the same relationship.
- The study suggests that urinary Klotho could serve as a potential biomarker for assessing kidney function in PD patients, but further research is needed to determine if these results apply to all chronic kidney disease patients.