Publications by Eri Ohmi

Publications by authors named "Eri Ohmi"

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DNA damage-induced CHK1 autophosphorylation at Ser296 is regulated by an intramolecular mechanism.

Naoyuki Okita Shota Minato Eri Ohmi Sei-ichi Tanuma Yoshikazu Higami

FEBS Lett

November 2012

CHK1 regulates the DNA damage-induced checkpoint involving an ATR- or ATM- dependent pathway. In this paper, we focused on the autophosphorylation of Ser296, one of the DNA damage-induced phosphorylation sites. First, we demonstrated that the Ser296 autophosphorylation of CHK1 is mainly regulated by an intramolecular mechanism in response to DNA damage.

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