Publications by authors named "Eri Iwata"

Background: The situation of Helicobacter pylori eradication therapy has been changing over time, owing to increases in antimicrobial-resistant strains, lifestyle improvements, and changes in indications for eradication. In Japan, eradication therapy is now available to all H. pylori-positive patients under the medical insurance system, and the potassium-competitive acid blocker vonoprazan has been used for eradication from 2015.

View Article and Find Full Text PDF

In the present study, the authors examined the association between gastric bacterial infection and gastric endoscopic findings in ()-negative patients. The subjects were 105 -negative patients. The mean age was 72.

View Article and Find Full Text PDF

Noma horses are native Japanese horses. Health checkups revealed that many Noma horses developed dermatitis during summer, which subsided in winter. Seasonal development and signs of itching, suggestive of allergic dermatitis, were observed.

View Article and Find Full Text PDF
Article Synopsis
  • Patients on hemodialysis (HD) are at risk for gastrointestinal diseases, and while eliminating Helicobacter pylori is advised to prevent gastric cancer, the best treatment approach and dosages for these patients remain unclear due to potential side effects and renal risks.
  • Some drugs used in eradication therapy, especially amoxicillin, can worsen kidney function, necessitating careful adjustment of dosages in HD patients.
  • Recent studies show that reducing drug dosages by 1/2 to 1/3 can minimize adverse effects while maintaining similar rates of successful eradication compared to healthy individuals, highlighting the need for optimized treatment regimens for this population.
View Article and Find Full Text PDF

Background: Map-like redness is a newly identified endoscopic risk factor for gastric cancer in patients who received Helicobacter pylori eradication therapy. However, the incidence rate of map-like redness in patients who received eradication, and the risk factors for the development of map-like redness remain unclear. We hence aimed to investigate the incidence rate of map-like redness at 1-year post H.

View Article and Find Full Text PDF

Plasma or serum amino acids are used to evaluate nutritional status and metabolic disorders. In this study, we aimed to set reference values of serum amino acid concentrations in the Noma horse, a Japanese native horse. Thirty-one horses were classified into six age groups: neonatal foal (0-4 days), foal (0.

View Article and Find Full Text PDF

Helicobacter pylori eradication therapy reduces the risk of gastric cancer. However, it is unclear whether the severity of risk factors for gastric cancer such as atrophy and intestinal metaplasia are reduced after eradication in the long term. We aimed to study long-term changes in endoscopic risk factors for gastric cancer up to 20 years post-eradication.

View Article and Find Full Text PDF

In this study, we investigated the relationship between the cecal intubation time (CIT) and the form and method used for passing through the sigmoid/descending colon junction (SDJ) and the hepatic flexure using an endoscopic position detection unit (UPD), with reference to various factors [age, sex, body mass index (BMI), history of abdominal and pelvic surgery, and diverticulum]. A total of 152 patients underwent colonoscopy with UPD. The mean age was 66.

View Article and Find Full Text PDF

The necropsy of a 2-day-old Noma horse that died of weakness showed an enlarged cardiac base and a narrow cardiac apex, suggesting cardiac malformation. The excised heart underwent imaging to investigate its luminal structure. On three-dimensional magnetic resonance imaging, the right atrium and right ventricle were discontinuous.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the impact of eradication therapy on patients with dyspepsia, focusing on short and long-term symptom improvement following treatment.
  • Results showed that about 34.5% of patients experienced symptom relief at 2 months post-eradication, and many maintained improvement up to 12 months.
  • Overall, the findings suggest that patients with dyspepsia associated with a specific infection should consider eradication therapy to reduce their symptoms effectively.
View Article and Find Full Text PDF

A 61-year-old -positive female with gastroesophageal reflux disease has undergone surveillance endoscopy every year for 13 years at Tokyo Medical University Hospital. At the first surveillance in 2009, conventional white light endoscopy showed a 10-mm whitish slightly depressed lesion at the lesser curvature of the gastric cardia. This lesion gradually increased in size to 15 mm over the 13-year observational period.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to determine if texture- and color-enhancement imaging (TXI) and narrow-band imaging (NBI) provide better results than white-light imaging (WLI) for diagnosing Barrett’s esophagus.
  • Researchers compared the endoscopic findings and color differences among 40 patients using WLI, TXI, and NBI, finding that NBI showed greater color differences compared to WLI.
  • Despite NBI's advantages in detecting color differences, TXI had a higher visibility score for Barrett's esophagus detection, suggesting both image-enhanced techniques are useful for evaluation compared to WLI alone.
View Article and Find Full Text PDF

Background: The use of an endoscopic position detection unit (UPD) enables better and more objective understanding of the shape and position of the colonoscope. Here, we investigated the reproducibility of the insertion of a colonoscope with UPD.

Materials And Methods: Study participants were 122 patients who received a colonoscopy with UPD twice for the purpose of large bowel screening and surveillance.

View Article and Find Full Text PDF
Article Synopsis
  • Getah virus (GETV), which is spread by mosquitoes and affects various animals, causes fever, rash, and leg edema in infected horses.
  • The study focused on Noma horses, a native breed in Japan, to investigate the occurrence of GETV infections among them.
  • Serum tests revealed that anti-GETV antibody levels in Noma horses were significantly higher in samples from 2017 compared to those from 2012, indicating an epidemic of GETV in Japan around 2012.
View Article and Find Full Text PDF

Noma horses have the smallest body size among native Japanese horses and are classified as pony breeds by their size. Additionally, the Japanese horse breeds are classified into a single lineage, which includes Mongolian horses. Great intraspecific differences reportedly exist in the head shapes of domesticated horses, which have been investigated in various horse breeds.

View Article and Find Full Text PDF
Article Synopsis
  • The study analyzes the relationship between age and blood test results or body sizes in Noma horses through health examinations.
  • It found significant but weak correlations in 14 out of 45 health indicators, with some decreasing (e.g., red blood cell count) and others increasing (e.g., body height) with age.
  • While some findings are unique to Noma horses, most changes in health indicators appear to be common trends seen across various horse breeds.
View Article and Find Full Text PDF

Background & Aims: Medication is a major determinant of human gut microbiome structure, and its overuse increases the risks of morbidity and mortality. However, effects of certain commonly prescribed drugs and multiple medications on the gut microbiome are still underinvestigated.

Methods: We performed shotgun metagenomic analysis of fecal samples from 4198 individuals in the Japanese 4D (Disease, Drug, Diet, Daily life) microbiome project.

View Article and Find Full Text PDF

In oral endoscopy, linked color imaging (LCI) detects atrophic border and gastric mucosal diseases better than white light imaging (WLI), but its usefulness in transnasal endoscopy has not been fully investigated. Here, we retrospectively compared WLI and LCI using the L*a*b* color space in images from 57 patients aged ≥20 years who had undergone transnasal endoscopy as part of a health check-up from May 2016 to January 2017. We measured color differences at the atrophic/non-atrophic and fundic/pyloric mucosal borders.

View Article and Find Full Text PDF

Background: Image-enhanced endoscopy methods such as narrow-band imaging (NBI) are advantageous over white-light imaging (WLI) for detecting gastric atrophy, intestinal metaplasia, and cancer. Although new third-generation high-vision ultrathin endoscopes improve image quality and resolution over second-generation endoscopes, it is unclear whether the former also enhances color differences surrounding atrophy and intestinal metaplasia for endoscopic detection. We compared the efficacy of a new third-generation ultrathin endoscope and an older second-generation endoscope.

View Article and Find Full Text PDF

Background: A new image-enhanced endoscopy method called texture and colour enhancement imaging (TXI) enhances brightness, surface irregularities, and subtle colour changes in endoscopic images. However, it is unclear whether TXI and narrow-band imaging (NBI) with third-generation high-vision transnasal ultrathin endoscopy are advantageous over white-light imaging (WLI) for detecting atrophy, intestinal metaplasia, map-like redness and gastric cancer. We investigated to compare the endoscopic efficacy for evaluation of gastritis between TXI and NBI with high-vision transnasal endoscopy and clarified the endoscopic efficacy of TXI and NBI compared to WLI.

View Article and Find Full Text PDF

Endoscopic population-based screening for gastric cancer began in April 2016, and the use of transnasal ultrathin esophagogastroduodenoscopy (UT-EGD) has rapidly become popular. With UT-EGD, discomfort associated with an examination is reduced, patient satisfaction is high, and adverse effects on cardiopulmonary function are fewer. Consequently, UT-EGD is a good option for gastric screening in an aging society.

View Article and Find Full Text PDF

The Kyoto gastritis classification is used to categorize the endoscopic characteristics of infection-associated gastritis. We aimed to clarify the association among endoscopic findings and abdominal dyspeptic symptoms in Japanese male. We administered a questionnaire to 418 subjects who underwent endoscopy as part of a health check-up from August 2003 to April 2004 to investigate the association among endoscopic findings of the Kyoto classification and the presence of dyspeptic symptoms.

View Article and Find Full Text PDF

is well known as a causative organism of cat scratch disease. Although this bacterium infrequently involves the heart, the diagnosis is difficult to confirm. A 75-year-old woman who had a pet cat presented with pancytopenia, hepatosplenomegaly, and low-grade fever.

View Article and Find Full Text PDF

Proton pump inhibitors (PPIs) are the first-line treatment for acid-related diseases. The pharmacokinetics and therapeutic efficacy of PPIs, however, are influenced by genetic factors such as variants in genes encoding drug-metabolizing enzymes (e.g.

View Article and Find Full Text PDF
Article Synopsis
  • Radiation causes increased capillary dilation and skin temperature in humans, and thermography can detect such changes after radiation therapy (RT).
  • In this study, a dog treated with RT for intranasal tumors showed a significant temperature rise in the nasal area after irradiation, while pain scores remained low and behavioral changes were minimal.
  • These findings highlight the importance of using objective methods like thermography for assessing pain in dogs post-RT, as traditional subjective evaluations may not fully capture their discomfort.
View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionpqa9q9762kpmivcaljerkfupjjcbsend): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once