Effect of Biopsychosocial Factors on Glycemic Control in Type 2 Diabetes Mellitus.

Objective: To investigate the effect of diabetic patients' biopsychosocial factors on type 2 diabetes mellitus (T2DM) outcomes to contribute to diabetes mellitus management.

Study Design: Cross-sectional descriptive study. Place and Duration of the Study: Department of Family Medicine, School of Medicine, Firat University, Turkey, from October 2021 to March 2022.

Evaluation of Serum ANGPTL8/Betatrophin and Cartonectin/CTRP3 Levels in Diabetic and Non-Diabetic Retinopathy.

Objective: To determine serum betatrophin and cartonectin levels and their relationship with biochemical parameters in diabetic and non-diabetic retinopathy.

Study Design: Descriptive study.

Place And Duration Of Study: Department of Internal Medicine and Ophthalmology, School of Medicine, Firat University, Turkey, from April to November 2020.

The role of trimethylamine-N-oxide level in the diagnosis of diabetic retinopathy and the differential diagnosis of diabetic and nondiabetic retinopathy.

Purpose: Trimethylamine N-oxide serum levels have been associated with type 2 diabetes mellitus and its complications. The current study aimed to find out if plasma trimethylamine N-oxide level may be a novel marker in the diagnosis of diabetic retinopathy and if it can be used in the differential diagnosis of diabetic and nondiabetic retinopathy.

Methods: The study included 30 patients with diabetic retinopathy, 30 patients with nondiabetic retinopathy, 30 patients with type 2 diabetes mellitus without retinopathy, and 30 healthy control participants.

mA RNA, FTO, ALKBH5 Expression in Type 2 Diabetic and Obesity Patients.

Objective: To investigate whether m6A content changes in type 2 diabetes mellitus (T2DM) and obese individuals and whether the relationship of m6A content with the mRNA expression levels of FTO and ALKBH5 genes.

Study Design: Cross-sectional study.

Place And Duration Of Study: Department of Internal Medicine, Firat University, Medical School, Elazig, Turkey, between January 2019 and January 2022.

Role of Betatrophin and Inflammation Markers in Type 2 Diabetes Mellitus, Prediabetes and Metabolic Syndrome.

Objective: To determine the association of betatrophin and inflammation factors in metabolic diseases such as diabetes, impaired fasting glucose, impaired glucose tolerance and metabolic syndrome.

Study Design: A cross-sectional, analytical study.

Place And Duration Of Study: Fırat University Medical School between April 2017 and December 2020.

Relationship between Serum Elabela Level and Hypertensıve Nephropathy.

Objective: To determine the difference in serum Elabela level in hypertensive patients with and without nephropathy compared to the healthy control group. Study Desing:  Cross-sectional descriptive study.

Place And Duration Of Study: Fırat University Medical School, Elazig, Turkey between December 2018 and November 2020.

Prevalence of Anemia and Associated Risk Factors among Pregnant Women, What is the Role of Antenatal Care in Prevention? A Cross-sectional Study.

Objective: To determine the prevalence of anemia with the associated factors in pregnant women and the effect of family medicine practice and antenatal care services provided by family physicians on the prevention of anemia during pregnancy.

Study Design: Community-based cross-sectional study.

Place And Duration Of Study: Family Health Centres in the Elazig region, Turkey from January to June 2019.

The Effects of Secondary Hyperparathyroidism on Circadian Blood Pressure in Hemodialysis Patients.

Objective: To determine the relationship between secondary hyperparathyroidism (sHPT) and circadian blood pressure (BP) rthym among patients undergoing hemodialysis treatment.

Study Design: A descriptive and prospective cohort study.

Place And Duration Of Study:   Department of Nephrology, Firat University Hospital, Turkey, between June and December 2019.

Comparison of stent and indomethacin suppository efficacy in the prevention of acute pancreatitis after ERCP.

Objective: We aimed to compare stent and indomethacin suppository efficacy in the prevention of acute pancreatitis after ERCP.

Materials And Methods: 76 high-risk patients undergoing ERCP were included in the study. The patients were divided into three groups as indomethacin group, stent group and control group.

Knowledge, behaviours and anxiety of eastern part of Turkey residents about the current COVID-19 outbreak.

Introduction: The aim of this study was to assess the knowledge, attitude, and behavior of Eastern part of Turkey residents about the COVID-19 and the relationship between the pandemic and the anxiety levels.

Methods: Cross-sectional study was carried out between 07-21 April 2020 through online questionnaires. The study included 897 people who filled out the form and met the study criteria.

Arterial Stiffness and its Related Factors in Patients on Hemodialysis.

Objective: To evaluate the prevalence of arterial stiffness in patients on hemodialysis and related factors that aggravate the condition.

Study Design: Prospective-cohort study.

Place And Duration Of Study:   Department of Nephrology, Firat University Hospital, Turkey, from August to October 2019.

Effects of vitamin D on apoptosis and betatrophin in the kidney tissue of experimental diabetic rats.

The aim of this study is to investigate the effects of vitD on betatrophin and apoptosis in rat kidney tissue using an experimental diabetes model created with STZ. 41 male Wistar-albino breed rat were assigned to 5 groups, which included 3 groups consisting of 7 animals each and 2 groups consisting of 10 animals each. The control group received no treatments.

Elabela levels in patients with type 2 diabetes: can it be a marker for diabetic nephropathy?

Background: Elabela (ELA) is a hormone that is secreted at high levels in the kidneys of a healthy adult. This study aims to investigate whether serum ELA levels of patients with Type 2 Diabetes vary with the severity of renal damage.

Methods: Our study included 50 healthy control subjects and 100 diabetic patients, who were categorized into groups based on urine albumin/creatinine ratios (ACR).

Analysis of Childhood Traumas and Defense Styles in Patients With Tension Headache.

Objective: Studies indicate that patients tend to develop chronic tension headache as a response to stress. The present study investigated the relationship between headache and the events that caused childhood traumas and defense styles, which could be considered as a significant source of stress in individuals with tension headache.

Methods: Fifty patients between the ages of 18 and 65 years diagnosed with tension headache were included in the present study.

Could neutrophil to lymphocyte ratio be a marker in Hashimoto's thyroiditis?

Objective: To determine the applicability of neutrophil/lymphocyte ratio as diagnostic and prognostic marker in patients with Hashimoto's thyroiditis.

Methods: The retrospective cross-sectional study was conducted at Elazig Firat University, Elazig, Turkey, and comprised data of Hashimato's thyroiditis patients aged 18 years or more admitted between January 1, 2017, and November 1, 2018. A healthy control group was also included to work as controls.

Serum apelin and resistin levels in patients with impaired fasting glucose, impaired glucose tolerance, type 2 diabetes, and metabolic syndrome.

Introduction: The aim of this study was to investigate serum apelin and resistin levels in patients with impaired fasting glucose, impaired glucose tolerance, type 2 diabetes and metabolic syndrome.

Material And Methods: The study comprised 18 patients with type 2 diabetes mellitus (T2DM) (nine females, nine males), 18 patients with impaired fasting glucose (IFG) (nine females, nine males), 18 patients with impaired glucose tolerance (IGT) (nine females, nine males), 18 patients with metabolic syndrome (MeS) (nine females, nine males), and 16 healthy individuals (eight females, eight males); serum adiponectin, apelin, resistin levels, fasting and postprandial blood glucose, insulin resistance markers, and lipid parameters were measured.

Results: In the study, serum apelin levels were determined to be significantly lower in IGT, MeS, and T2DM groups compared with the control group (p = 0.

Low serum levels of meteorin-like/subfatin: an indicator of diabetes mellitus and insulin resistance?

Introduction: Meteorin-like (Metrnl), also known as subfatin, is a recently discovered adipokine with a favourable effect on insulin sensitivity. Studies have shown lower Metrnl levels in obese patients. However, data on its circulating levels in type 2 diabetes mellitus (T2DM) patients are contradictory.

Neutrophil and platelet to lymphocyte ratio in patients with hypothyroid Hashimoto's thyroiditis.

Aim: Chronic lymphocytic thyroiditis is among the most common causes of hypothyroidism along with HT (Hashimoto's thyroiditis) goitre, which is also named as autoimmune thyroiditis. Our study aims to determine the usefulness of PLR (platelet to lymphocyte ratio) and NLR (neutrophil to lymphocyte ratio), which can be obtained with a hemogram, at the clinical course or the severity of the disease in patients with Hashimoto's thyroiditis.

Materials And Methods: Our study is a retrospective cross-sectional study that included 121 hypothyroid or subclinical hypothyroid Hashimoto's thyroiditis patients and a healthy control group comprised of 100 individuals.

An investigation of saliva and plasma levels of urotensin 2 in recently diagnosed type 2 diabetes mellitus patients on metformin treatment.

Introduction: Diabetes mellitus (DM) is a primary disease of the carbohydrate metabolism that is characterised by absolute or relative insulin deficiency, or insulin resistance. Although life expectancy is low for diabetic patients, the prognosis has been improved in recent decades. Metformin is an oral antidiabetic that reduces insulin resistance and plasma glucose levels by decreasing glucose production in the liver.

Can hematological parameters in type 2 diabetes predict microvascular complication development?

Objective: To examine potential associations between neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, mean platelet volume (MPV), HbA1c and microvascular complications in diabetic patients from a cost-effectiveness perspective.

Methods: One hundred patients with type 2 diabetes attending our outpatient unit between May 2018 and October 2018 were included, and 100 healthy individuals served as the control group. A retrospective file search was performed to collect information on hemoglobin, mean platelet volume (MPV), glycosylated haemoglobin (HbA1c), hematocrit (Hct), neutrophil and lymphocyte count, neutrophil/lymphocyte ratio (NLR), platelets (Plt), platelet/lymphocyte ratio (PLR), and microvascular complications (neuropathy, retinopathy, nephropathy).

Hypercalcemia related to cholangiocellular carcinoma.

Patients with malignancies may develop hypercalcemia due to bone metastases or paraneoplastic reasons. Hepatocellular cancer should be considered in liver masses detected in chronic viral hepatitis B patients with delta agents. However, in our case, we detected cholangiocellular carcinoma in the etiology of hypercalcemia.

The relationship between monocyte to high-density lipoprotein cholesterol ratio and diabetic nephropathy.

Objective: This study aims to investigate the relationship of monocyte to high-density lipoprotein cholesterol ratio (MHR) with diabetes mellitus (DM) and diabetic nephropathy.

Methods: This study included 262 Type-2 diabetes mellitus patients, of which 60 had diabetic nephropathy and 202 did not have diabetic nephropathy who presented to the internal diseases polyclinic at Firat University Medical Faculty Hospital between May 2018 and October 2018 and 50 healthy control subjects. A retrospective scan of patient files was conducted and information relevant to nephropathy such as hemoglobin, glycated hemoglobin levels (HbA1c), hematocrit count (HCT), monocyte count, LDL, HDL, triglyceride levels, and microvascular complications were acquired.