Antibacterial Effects of the Novel Blue Laser and Erbium Chromium Laser on Faecalis in Root Canal Dentin with Different Thicknesses.

The aim of this study was to investigate the antibacterial effects of 445 nm blue diode lasers and erbium chromium lasers on the biofilm of in root canal dentin with different thicknesses. Dentin slices with thicknesses of 300, 500, and 1,000 microns were prepared; and after the biofilm formation, they were randomly divided into four groups: group A : Er, Cr:YSGG laser radiation; group B: 445 nm diode laser radiation; group C : laser radiation in three cycles; and control group D: 5 samples of each thickness were selected as a positive control group. Er, Cr:YSGG and diode lasers alone did not significantly reduce the number of bacteria in any of the thicknesses.

Effect of biodentine coated with emdogain on proliferation and differentiation of human stem cells from the apical papilla.

Background: This study assessed the effect of Biodentine coated with Emdogain (Biodentine/Emdogain) on proliferation and differentiation of human stem cells from the apical papilla (SCAPs). METHODS AND RESULTS: In this in vitro, experimental study, SCAPs were isolated from two immature impacted third molars and cultured. After ensuring the stemness of the cells by assessing the cell surface markers, they were exposed to Biodentine, Emdogain, and Biodentine/Emdogain for 24 and 72 h.