Publications by authors named "Eren Ekici"
Article Synopsis
- * By 2040, over 110 million people aged 40 to 80 are projected to be affected by glaucoma, presenting a major economic burden, and it can be categorized into various forms such as open-angle and angle-closure.
- * Understanding the complex biological mechanisms behind glaucoma, including factors like elevated IOP, aging, and neuroinflammation, is vital for developing effective treatments, as the disease often progresses silently, ultimately leading to irreversible visual impairment.
Consecutive central and branch retinal vein occlusions in the same eye of a young healthy COVID-19 patient: A unique case report.
Am J Ophthalmol Case Rep
September 2022
Purpose: To report a case of consecutive central retinal vein occlusion (CRVO) and branch retinal vein occlusion (BRVO) in the same eye correlated with coronavirus disease (COVID-19) of the otherwise healthy patient.
Observations: A 39-year-old woman with the diagnosis of COVID-19 infection for two weeks presented with a nonischemic central retinal vein occlusion (CRVO) in her right eye. The patient was on low-dose aspirin for anticoagulant prophylaxis (100 mg/day) for a week when the CRVO occurred.
Purpose: To compare the repeatability and reproducibility of the Schirmer test (ST) without anesthesia when the eyes are open (STo) and closed (STc) in previously undiagnosed patients with suggestive symptoms of dry eye.
Methods: In a comparative, observational series case study, 31 patients were included in the study. STo and STc were alternately applied for a total of six times.
Purpose: To study the effect of topical bimatoprost on the corneal optical density values using a dual Scheimpflug Placido analysis system.
Methods: This longitudinal case-control study included 18 patients with newly diagnosed primary open-angle glaucoma who received topical bimatoprost as a first-line treatment and 20 healthy individuals (age and sex-matched controls). Corneal densitometry data were obtained using the dual Scheimpflug analyzer at pre-treatment and 1st, 6th, 12th, 18th months of post-treatment.
Macular Thickness and Microvasculature Loss in Glaucoma Suspect Eyes.
Ophthalmol Glaucoma
April 2022
Purpose: To characterize the change of ganglion cell complex (GCC) thickness and macular vessel density in glaucoma suspect eyes with ocular hypertension (OHT) or glaucomatous optic neuropathy (GON).
Design: Prospective, longitudinal study.
Participants: Eight-three eyes (24 healthy, 30 OHT, and 29 GON) of 65 patients who underwent at least 3 visits were included from the Diagnostic Innovations in Glaucoma Study.
Purpose: To compare spectral-domain optical coherence tomography (SDOCT) measured circumpapillary retinal nerve fiber layer (cpRNFL) among 4 glaucomatous optic disc phenotypes in early glaucoma.
Design: Clinical cohort study METHODS: In this study, 218 early glaucoma eyes that had at least 3 years of follow-up and a minimum of 4 SDOCT scans were recruited. The optic discs were classified into 4 types based on appearance: 76 generalized cup enlargement (GE), 53 focal ischemic (FI), 22 myopic glaucomatous (MY), and 67 senile sclerotic (SS).
Precis: Macular superficial capillary plexus (SCP) vessel density is more informative than deep capillary plexus (DCP) vessel density for the detection of glaucoma.
Purpose: The purpose of this study was to characterize optical coherence tomography angiography macular SCP and projection-resolved DCP vessel densities and compare their diagnostic accuracies with ganglion cell complex (GCC) thickness in healthy, glaucoma suspect, and glaucoma eyes.
Materials And Methods: Sixty-eight eyes of 44 healthy subjects, 26 eyes of 16 preperimetric glaucoma suspects, and 161 eyes of 124 glaucoma patients from the Diagnostics Innovations in Glaucoma Study with good quality high-density 6×6 mm2 macula optical coherence tomography angiography images were included.
Purpose: To determine the prevalence of different types of artifacts seen in OCT angiography (OCTA) images of healthy and glaucoma eyes and evaluate the characteristics associated with poor-quality images.
Design: Retrospective study.
Participants: A total of 649 eyes of 368 healthy, glaucoma suspect, and glaucoma patients.
Purpose: To investigate central visual field (VF) defects among 4 phenotypes of glaucomatous optic discs.
Design: Cross-sectional study.
Methods: Optic disc phenotypes were determined in eyes with definite or suspected glaucoma that had a 24-2 VF with mean deviation (MD) better than -12 dB and a 10-2 VF.
Purpose: To evaluate racial differences in optic nerve head peripapillary capillary density measured by OCT angiography (OCTA) in patients with open-angle glaucoma.
Design: Observational, cross-sectional study.
Participants: Two hundred eighty-four eyes of 195 glaucoma patients and 108 eyes of 58 healthy participants from the Diagnostic Innovations in Glaucoma Study.
Purpose: To compare optical coherence tomography angiography (OCTA)-measured capillary density of the optic disc among 4 glaucomatous optic disc phenotypes.
Design: Cross-sectional study.
Methods: Circumpapillary capillary density (cpCD) of 4 glaucomatous optic disc phenotypes in 193 eyes of 141 glaucoma patients and cpCD in 92 eyes of 55 healthy subjects from the Diagnostic Innovations in Glaucoma Study (DIGS) were compared.
Purpose: To investigate the relationship between corneal hysteresis (CH) and anterior lamina cribrosa surface (ALCS) displacement over time in a cohort of patients with glaucoma.
Design: Prospective observational case series.
Methods: In this study, 147 eyes from 96 glaucoma or glaucoma suspect patients were followed for a mean of 3.