Publications by authors named "Erea-Noel Garabedian"

Objective: The objective was to assess Potsic, EAONO/JOS, STAMCO, and ChOLE cholesteatoma staging systems in a large homogenous pediatric cohort with long-term follow-up and propose an evidence-based improved version.

Study Design: Cohort study.

Setting: Retrospective study in a tertiary referral center.

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Article Synopsis
  • The study aimed to create a comprehensive definition of a surgeon by gathering perspectives from patients, healthcare workers, and surgeons.
  • An online questionnaire collected respondents' views on essential qualities and shortcomings of surgeons, analyzing responses based on themes like human qualities, technical skills, and knowledge.
  • Key findings showed dexterity as the top quality, but emphasized that human traits, especially empathy, are crucial; also, surgeons valued knowledge more than non-surgeons did, indicating a need for better recognition of this aspect.
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Objective: To evaluate the accuracy, sensitivity, and specificity of nonecho planar (non-EPI) diffusion-weighted (DW) magnetic resonance imaging (MRI) to detect residual cholesteatoma in children.

Study Design: Retrospective study.

Setting: Tertiary comprehensive hospital.

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Objective: Non-echo-planar diffusion-weighted (DW) magnetic resonance imaging (non-EPI MRI) is the appropriate sequence to detect residual cholesteatoma. In the child, MRI may be clinically useful to determine the timing of the second-look procedure. The aim of this paper was to retrospectively evaluate the performance of early MRI (before the 18th postoperative month) in detecting residual cholesteatoma in children after review by experienced specialized neuroradiologists.

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This research letter compares computed tomography and magnetic resonance imaging in the 1-year second-stage diagnosis of cholesteatoma.

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Objective: Microtia is a congenital auricular malformation, often part of a syndromic form (35%-55% of cases). The accurate prevalence of associated malformations remains to be determined with regard to the heterogeneous results of the previous studies. This study aims to describe in a large population cohort the abnormalities associated with microtia and to determine the most suitable assessment for these children.

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Age at implantation is considered to be a major factor, influencing outcomes after pediatric cochlear implantation. In the absence of acoustic input, it has been proposed that cross-modal reorganization can be detrimental for adaptation to the new electrical input provided by a cochlear implant. Here, through a retrospective study, we aimed to investigate differences in cerebral blood flow (CBF) at rest prior to implantation in children with congenital deafness compared to normally hearing children.

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Purpose: To report our experience with endoscopic Thulium LASER for treatment of recurrent TEF after EA surgery, and for H-Type fistulas.

Methods: A retrospective chart review of consecutive patients undergoing standardized endoscopic closure as first line therapy of recurrent tracheoesophageal fistula (RTEF) and H-type fistula using Thulium LASER, from 2013 to 2019, in a pediatric tertiary care center. Control endoscopic procedure was systematically performed.

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Background: Knowledge about airway dimensions during child growth is of paramount importance for pediatric clinical practice. Decisions about airway management in children are based on relatively limited, imprecise, or incomplete data about airway size.

Aims: The aim of this work was to determine the anatomical development and size of airway structures from birth to adolescence using high-resolution computed tomography scans and to study the correlation between airway measurements and biometric data.

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Objective: To provide recommendations to otolaryngologists and allied physicians for the comprehensive management of children who present with signs and symptoms of congenital cholesteatoma.

Methods: A two-iterative Delphi method questionnaire was used to establish expert recommendations by the members of the International Pediatric Otolaryngology Group, on the preoperative work-up, the perioperative considerations, and follow-up.

Results: Twenty-two members completed the survey, in 14 tertiary-care center departments representing 5 countries.

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Introduction: Desmoid-type fibromatosis (DF) is a rare benign lesion known for its local aggressiveness. The tumor management still remains under debate. Primary head and neck (HN), represents the second most prevalently affected sitein children with DF.

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Article Synopsis
  • Reunion Island has a higher prevalence of deafness (1.6/1000) compared to mainland France, with a study involving twelve children who have isolated bilateral prelingual profound deafness and vestibular issues.
  • These children had normal results in electroretinography and temporal bone CT scans, and a novel genetic mutation (LHFPL5) was identified through whole-exome sequencing in several families.
  • The presence of the same genetic variant in multiple families is linked to a common ancestor from 1693, and the patients' condition resembles a known murine model of hearing loss.
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Introduction: The diagnosis and management of type I laryngeal clefts can be controversial and varies across centers and surgeons. Using existing peer-reviewed literature to develop an expert-based consensus will help guide physicians in the treatment of these patients as well as develop research hypotheses to further study this condition.

Objective: To provide recommendations for the diagnosis and management of type I laryngeal clefts.

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  • The study investigates the causes of unilateral sensorineural hearing loss (USNHL) in children, highlighting its impact on academic and social skills.
  • The analysis of 80 children shows that a significant portion had profound hearing loss, with notable cases of inner ear malformations and cochlear nerve deficiency.
  • The conclusion calls for ongoing hearing assessments, recommends MRI for better diagnosis, suggests systematic screening for cytomegalovirus, and emphasizes the need for more genetic research related to USNHL.
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Objective(s): To describe a new and more simple surgical procedure for implanting the Vibrant Soundbridge (VSB) on the short process of the incus in children with ear atresia and atretic plate and present the audiometric results.

Methods: Since 2014, pre- and post-operative audiometric tests with tonal and vocal audiometryat the maximal follow up, respectively 33, 22 and 12 months were performed after VSB implantation at the ENT department, Necker Enfants Malades Hospital, Paris, France. 3 children aged 11, 9 and 15 years with conductive hearing loss due to high grade ear atresia and absent ear canal were implanted.

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Objective: Cryptotia is one of the most common malformations of the upper auricle with aesthetic and functional consequences, however there is no standard treatment. We present the surgical technique and results of a kite flap procedure which can be used in the different cryptotia subtypes.

Methods: We reviewed all patients treated in our department from 2010 to 2015, using a mastoid fascia kite flap technique.

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Perrault syndrome (PS) is a rare autosomal recessive condition characterized by deafness and gonadic dysgenesis. Recently, mutations in five genes have been identified: C10orf2, CLPP, HARS2, HSD17B4, and LARS2. Probands included are presented with sensorineural deafness associated with gonadic dysgenesis.

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Purpose: Outpatient pediatric audiometry brainstem response (ABR) uses various techniques (no drug, hydroxyzine, pentobarbital, melatonin). The aim of this study was to evaluate the efficiency of melatonin as compared to pentobarbital in children with associated disorders.

Method: This was a retrospective study that took place in a tertiary care center.

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Objectives/hypothesis: To analyze clinical presentations, treatment modalities, and evolution of pediatric cases of salivary gland carcinomas to standardize care for these rare diseases.

Study Design: Multicentric, retrospective study.

Methods: We included in this retrospective study all children and adolescents (aged ≤18 years) treated from 1992 to 2012 in six pediatric centers in Paris, France.

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Lymphatic malformations are benign malformations frequently occurring in the head and neck. Retropharyngeal location is rare, can be life threating and its management is particularly challenging. Over a three-year period, three patients presented with symptomatic (dyspnea and/or dysphagia) retropharyngeal lymphatic malformation.

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Unlabelled: The aim of the study was to evaluate noninvasive continuous positive airway pressure as first-line treatment for upper airway obstruction in neonates with Pierre Robin sequence. Forty-four neonates were enrolled and classified in 4 groups: ventilator-dependent patients (severe upper airway obstruction group), patients with clinical upper airway obstruction, an abnormal (moderate upper airway obstruction group) or normal polygraphy (mild upper airway obstruction group), and those with no clinical upper airway obstruction (no upper airway obstruction group). Five neonates in the severe upper airway obstruction group (n = 9) were successfully managed by noninvasive continuous positive airway pressure and 4 required a tracheotomy.

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The present work report cases of auricular burns after routine otologic surgery possibly induced by the operating microscope. Single-center retrospective study. April 2013 to January 2014, eight children presented with auricular burns after otologic surgery.

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We discuss a case of severe respiratory depression in a child, with ultrarapid CYP2D6 genotype and obstructive sleep apnea syndrome, after taking tramadol for pain relief related to a day-case tonsillectomy.

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