Effect of Prophylactic Negative-Pressure Wound Therapy for High-Risk Wounds in Colorectal Cancer Surgery: A Randomized Controlled Trial.

Objective: To determine the effect of prophylactic negative-pressure wound therapy (pNPWT) in patients at high risk of surgical wound complications (SWCs) who underwent colorectal cancer (CRC) surgery.

Methods: In an open-label randomized controlled trial, 50 patients who underwent open CRC surgery between November 2018 and February 2020 were included. Participants were randomly assigned to the pNPWT group (n = 24) or control group (n = 26).