Publications by authors named "Erdan Xin"

Ethnopharmacological Relevance: The herb pair Astragali Radix (AR) and Curcumae Rhizoma (vinegar-processed, VPCR), derived from the traditional Chinese medicine (TCM) text 'Yixuezhongzhongcanxilu', have long been used to treat gastrointestinal diseases, notably colitis-associated colorectal cancer (CAC). Hedysari Radix (HR), belonging to the same Leguminosae family as AR but from a different genus, is traditionally used as a substitute for AR when paired with VPCR in the treatment of CAC. However, the optimal compatibility ratio for HR-VPCR against CAC and the underlying mechanisms remain unclear.

View Article and Find Full Text PDF

Context: Hedysari Radix Praeparata Cum Melle (HRPCM) and Astragali Radix Praeparata Cum Melle (ARPCM) are used interchangeably in clinics to treat spleen-qi deficiency (SQD) symptom mainly including gastrointestinal dysfunction and decreased immunity, which has unknown differences in efficacy.

Objective: To investigate the differences between HRPCM and ARPCM on intervening gastrointestinal- and immune-function with SQD syndrome.

Materials And Methods: After the SQD model was established, the Sprague-Dawley (SD) rats were randomly divided into nine groups ( = 10): normal; model; Bu-Zhong-Yi-Qi Pills; 18.

View Article and Find Full Text PDF
Article Synopsis
  • - The study aimed to investigate the chemical changes that occur in Hedysari Radix (HR) before and after being processed with honey (HPHR) and how these changes affect their efficacy in treating spleen qi deficiency.
  • - An analysis using UPLC-MS revealed that HPHR contained a different composition of compounds compared to HR, showing that honey-processing influences the therapeutic properties of Hedysari Radix.
  • - Results indicated that both HR and HPHR improved conditions related to spleen qi deficiency in rats, but HPHR was found to be more effective, as evidenced by better protective effects on spleen tissue and more favorable serum biomarker levels.
View Article and Find Full Text PDF