Purpose: In biotechnology, microscopic cell imaging is often used to identify and analyze cell morphology and cell state for a variety of applications. For example, microscopy can be used to detect the presence of cytopathic effects (CPE) in cell culture samples to determine virus contamination. Another application of microscopy is to verify clonality during cell line development.
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July 2012
Ultrasonic detection and characterization of targets concealed by scattering noise is remarkably challenging. In this study, a neural network (NN) coupled to split-spectrum processing (SSP) is examined for target echo visibility enhancement using experimental measurements with input signal-to-noise ratio around 0 dB. The SSP-NN target detection system is trainable and consequently is capable of improving the target-to-clutter ratio by an average of 40 dB.
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June 2009
In this study, we address the increased computational demands of a frequency-diverse ultrasonic target detection system by developing a zero-phase IIR (ZP-IIR) filter. Several ZP-IIR filter types including Chebyshev-I, Chebyshev- II, and Butterworth were analyzed for their detection performance. The 4th-order filters with 8-bit quantized coefficients are shown to improve the flaw-to-clutter ratio by approximately 10 dB.
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