Publications by authors named "Erdal Horata"
Article Synopsis
- Autism spectrum disorders (ASDs) are neurodevelopmental conditions marked by social skill deficits and abnormal sensory responses, with an imbalance of excitation and inhibition in the brain being a crucial factor.
- This study examined the levels of key neurotransmitters (GABA, glutamate, and serotonin) in the thalamus of rats induced with ASD using valproic acid (VPA) during pregnancy.
- Results showed that ASD rats had higher serotonin levels, altered thalamic volumes, and fewer thalamic neurons and glia compared to the control group, suggesting a disrupted neurotransmitter balance in the thalamus related to ASD.
The contribution of the thalamus to the development and behavioural changes in autism spectrum disorders (ASD), a neurodevelopmental syndrome, remains unclear. The aim of this study was to determine the changes in thalamic volume and cell number in the valproic acid (VPA)-induced ASD model using stereological methods and to clarify the relationship between thalamus and ASD-like behaviour. Ten pregnant rats were administered a single dose (600 mg/kg) of VPA intraperitoneally on G12.
View Article and Find Full Text PDFNausea and vomiting during pregnancy are common problems and prolonged pharmacological treatment often is needed; however, the teratogenic effects of anti-emetic drugs on neural tube (NT) development are not clear. We investigated the effects of different doses of metoclopramide on NT development in 48 and 72 h chick embryos using an argyrophilic nucleolar organizing region (AgNOR) staining method. We used 150 fertile, specific pathogen-free eggs incubated for 28 h, then randomly divided into five equal groups: group A, sham control was administered 0.
View Article and Find Full Text PDFBackground: In task-oriented studies showed that the chronic pain is effective on dual tasks. Chronic pain is the main health problem that prevents mobility restriction and participation in most rheumatic diseases.
Research Question: Do rheumatic diseases have an effect on dual task gait performance?
Methods: This comparative-descriptive study included 75 individuals who aged 18-65 years and divided in two groups as Rheumatic Disease Group (RG; 23 women, 14 men) and Control Group (CG; 20 women, 18 men).
Aim: To examine foramen magnum morphometry and shape of Chiari malformation in comparison with a control group, and to contribute to the literature on whether Chiari malformation affects foramen magnum morphometry.
Material And Methods: In this study, cranial magnetic resonance images of 71 people with Chiari malformation and 61 people as controls were examined. The anteroposterior diameter, transverse diameter, and area of the foramen magnum were measured, and the shape of the foramen magnum was determined.
Purpose: The primary approach to treating large cystic lesions is controversial. The aims of the present study were to assess the effects of decompression before enucleation for the treatment of large cystic lesions and to compare the rate of decrease of keratocystic odontogenic tumor, ameloblastoma, and dentigerous cyst at specific times (preoperatively and at 6 months).
Patients And Methods: The study included 40 patients (mean age, 31.
Purpose: The human pineal gland is a small neuroendocrine organ which produces melatonin. The main goal of this study was to provide a reference range for pineal volume in all age groups and to determine calcified and noncalcified tissue and their proportions, which may be a reflection of melatonin production in all age groups, by using very thin computerized tomography (CT) slices.
Materials And Methods: A total of 167 outpatients had undergone cranial CT.